Publications-2023 - M3 Research Group

Publications 2023

Hendriks FK, Trommelen J, van der Sande FM, van Kranenburg JMX, Kuijpers JHW, Houtvast DCJ, Jetten GHJ, Goessens JPB, Meex SJR, Kooman JP, van Loon LJC. Branched‐chain ketoacid co‐ingestion with protein lowers amino acid oxidation during hemodialysis: A randomized controlled cross‐over trial.
Clin Nutr. 2023;42(8):1436‐44 https://www.ncbi.nlm.nih.gov/pubmed/37441814 [IF: 6.3].

Weijzen MEG, Holwerda AM, Jetten GHJ, Houben LHP, Kerr A, Davis H, Keogh B, Khaldi N, Verdijk LB, van Loon LJC. Vicia Faba peptide network supplementation does not differ from milk protein in modulating changes in muscle size during short‐term immobilization and subsequent remobilization, but increases muscle protein synthesis rates during remobilization in healthy young men. J Nutr. 2023;153(6):1718‐29 https://www.sciencedirect.com/science/article/pii/S0022316623025166 [IF:5.784].

Pinckaers PJM, Kouw IWK, Gorissen SHM, Houben LHP, Senden JM, Wodzig W, de Groot L, Verdijk LB, Snijders T, van Loon LJC. The Muscle Protein Synthetic Response to the Ingestion of a Plant‐Derived Protein Blend Does Not Differ from an Equivalent Amount of Milk Protein in Healthy Young Males. J Nutr. 2023;152(12):2734‐43 https://www.ncbi.nlm.nih.gov/pubmed/36170964 [IF:5.784].

Hermans WJ, Fuchs CJ, Nyakayiru J, Hendriks FK, Houben LH, Senden JM, van Loon LJC, Verdijk LB. Acute Quark Ingestion Increases Muscle Protein Synthesis Rates at Rest with a Further Increase after Exercise in Young and Older Adult Males in a Parallel‐Group Intervention Trial. J Nutr. 2023;153(1):66‐75
https://www.ncbi.nlm.nih.gov/pubmed/36913480 [IF: 5.784].

Houben LHP, Overkamp M, van Kraaij P, Trommelen J, van Roermund JGH, de Vries P, de Laet K, van der Meer S, Mikkelsen UR, Verdijk LB, van Loon LJC, Beijer S, Beelen M. Resistance Exercise Training Increases Muscle Mass and Strength in Prostate Cancer Patients on Androgen Deprivation Therapy. Med Sci Sports Exerc. 2023;55(4):614‐24 https://www.ncbi.nlm.nih.gov/pubmed/36534950 [IF: 5.411].

Hilkens L, van Schijndel N, Weijer V, Boerboom M, van der Burg E, Peters V, Kempers R, Bons J, van Loon LJC, van Dijk JW. Low Bone Mineral Density and Associated Risk Factors in Elite Cyclists at Different Stages of a Professional Cycling Career. Med Sci Sports Exerc. 2023;55(5):957‐65 https://www.ncbi.nlm.nih.gov/pubmed/36595659 [IF: 5.411].

Aussieker T, Hilkens L, Holwerda AM, Fuchs CJ, Houben LHP, Senden JM, van Dijk JW, Snijders T, van Loon LJC. Collagen Protein Ingestion during Recovery from Exercise Does Not Increase Muscle Connective Protein Synthesis Rates. Med Sci Sports Exerc. 2023;55(10):1792‐802 https://www.ncbi.nlm.nih.gov/pubmed/37202878 [IF: 5.411].

Trommelen J, van Lieshout GAA, Pabla P, Nyakayiru J, Hendriks FK, Senden JM, Goessens JPB, van Kranenburg JMX, Gijsen AP, Verdijk LB, de Groot L, van Loon LJC. Pre‐sleep Protein Ingestion Increases Mitochondrial Protein Synthesis Rates During Overnight Recovery from Endurance Exercise: A Randomized Controlled Trial. Sports Med. 2023;53(7):1445‐55 https://www.ncbi.nlm.nih.gov/pubmed/6857005 [IF: 5.7].

Parr EB, Kouw IWK, Wheeler MJ, Radford BE, Hall RC, Senden JM, Goessens JPB, van Loon LJC, Hawley JA. Eight‐hour time‐restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized control trial. Obesity (Silver Spring). 2023;31 Suppl 1(Suppl 1):116‐26 https://www.ncbi.nlm.nih.gov/pubmed/36546330 [IF: 5.002].

Joosten IBT, Fuchs CJ, Beelen M, Plasqui G, van Loon LJC, Faber CG. Energy Expenditure, Body Composition, and Skeletal Muscle Oxidative Capacity in Patients with Myotonic Dystrophy Type 1. J Neuromuscul Dis. 2023;10(4):701‐12 https://www.ncbi.nlm.nih.gov/pubmed/37154183 [IF: 4.693].

van Lieshout GAA, Trommelen J, Nyakayiru J, van Kranenburg J, Senden JM, Verdijk LB, van Loon LJC. The Postprandial Plasma Amino Acid Response Does Not Differ Following the Ingestion of a Solid Versus a Liquid Milk Protein Product in Healthy Adult Females. Int J Sport Nutr Exerc Metab. 2023;33(5):247‐54 https://www.ncbi.nlm.nih.gov/pubmed/37348850 [IF: 4.599].

McCarthy DG, Bone J, Fong M, Pinckaers PJM, Bostad W, Richards DL, van Loon LJC, Gibala MJ. Acute Ketone Monoester Supplementation Impairs 20‐min Time‐Trial Performance in Trained Cyclists: A Randomized, Crossover Trial. Int J Sport Nutr Exerc Metab. 2023;33(4):181‐8 https://www.ncbi.nlm.nih.gov/pubmed/37185454 [IF: 4.599].

Hendriks FK, Kuijpers JHW, van Kranenburg JMX, Senden JMG, van der Sande FM, Kooman JP, Meex SJR, van Loon LJC. Intradialytic Protein Ingestion and Exercise do Not Compromise Uremic Toxin Removal Throughout Hemodialysis. J Ren Nutr. 2023;33(2):376‐85 https://www.ncbi.nlm.nih.gov/pubmed/35988911 [IF: 4.354].

Hilkens L, Boerboom M, van Schijndel N, Bons J, van Loon LJC, van Dijk JW. Bone turnover following high‐impact exercise is not modulated by collagen supplementation in young men: A randomized cross‐over trial. Bone. 2023;170:116705 https://www.ncbi.nlm.nih.gov/pubmed/36804484 [IF: 4.147].

Hendriks FK, Weijzen MEG, Goessens JPB, Zorenc AHG, Gijsen AP, Kramer IF, van den Bergh JPW, Poeze M, Blokhuis TJ, van Loon LJC. Trabecular, but not cortical, bone tissue protein synthesis rates are lower in the femoral head when compared to the proximal femur following an intracapsular hip fracture. Bone. 2023;177:116921 https://www.ncbi.nlm.nih.gov/pubmed/37769955 [IF: 4.147].

Krakova D, Holwerda AM, Betz MW, Lavin KM, Bamman MM, van Loon LJC, Verdijk LB, Snijders T. Muscle fiber type grouping does not change in response to prolonged resistance exercise training in healthy older men. Exp Gerontol. 2023;173:112083 https://www.ncbi.nlm.nih.gov/pubmed/36621699 [IF: 4.032].

Fuchs CJ, Kuipers R, Rombouts JA, Brouwers K, Schrauwen‐Hinderling VB, Wildberger JE, Verdijk LB, van Loon LJC. Thigh muscles are more susceptible to age‐related muscle loss when compared to lower leg and pelvic muscles. Exp Gerontol. 2023;175:112159 https://www.ncbi.nlm.nih.gov/pubmed/36967049 [IF: 4.032].

Vandenabeele F, Stevens S, Snijders T, Stessel B, Dubois J, van Loon LJC, Lambrichts I, Agten A. Observations of nemaline bodies in muscle biopsies of critically ill patients infected with SARS‐CoV‐2. Microscopy (Oxf). 2023;72(5):388‐94 https://www.ncbi.nlm.nih.gov/pubmed/36574223 [IF: 1.571].

Overkamp M, Houben LHP, van der Meer S, van Roermund JGH, Bos R, Kokshoorn APJ, Larsen MS, van Loon LJC, Beelen M, Beijer S. Onset of androgen deprivation therapy leads to rapid deterioration of body composition, physical performance, cardiometabolic health and quality‐of‐life in prostate cancer patients. Scand J Urol. 2023;57(1‐6):60‐6 https://www.ncbi.nlm.nih.gov/pubmed/36703515 [IF: 1.37].

Overkamp M, Houben LHP, Aussieker T, van Kranenburg JMX, Pinckaers PJM, Mikkelsen UR, Beelen M, Beijer S, van Loon LJC, Snijders T. Resistance Exercise Counteracts the Impact of Androgen Deprivation Therapy on Muscle Characteristics in Cancer Patients. J Clin Endocrinol Metab. 2023;108(10):e907‐e15, https://www.ncbi.nlm.nih.gov/pubmed/37161470 [IF: 6.134].

Trommelen J, van Lieshout GAA, Nyakayiru J, Holwerda AM, Smeets JSJ, Hendriks FK, van Kranenburg JMX, Zorenc AH, Senden JM, Goessens JPB, Gijsen AP, van Loon LJC. The anabolic response to protein ingestion during recovery from exercise has no upper limit in magnitude and duration in vivo
in humans. Cell Rep Med. 2023;4(12):101324, https://www.ncbi.nlm.nih.gov/pubmed/38118410

van Loon LJC, Trommelen J, Geissler C, Powers H. Dietary considerations for sport and exercise Human Nutrition. Dietary considerations for sport and exercise. 14 ed. Oxford: Oxford University Press; 2023. Book Chapter 18, p. 808. https://www.oxfordsciencetrove.com/display/10.1093/hesc/9780198866657.001.0001/isbn-9780198866657-chapter-18

23 Publications

All publications by year

2024

Pinckaers, Philippe J. M., Joey S. J. Smeets, et al. ‘Post-Prandial Muscle Protein Synthesis Rates Following the Ingestion of Pea-Derived Protein Do Not Differ from Ingesting an Equivalent Amount of Milk-Derived Protein in Healthy, Young Males’. European Journal of Nutrition, vol. 63, no. 3, Jan. 2024, pp. 893–904, https://doi.org10.1007/s00394-023-03295-6.

Houben, Lisanne H. P., Tom Tuytten, et al. ‘A Low or High Physical Activity Level Does Not Modulate Prostate Tumor Tissue Protein Synthesis Rates’. Medicine and Science in Sports and Exercise, vol. 56, no. 4, Nov. 2023, pp. 635–643, https://doi.org10.1249/MSS.0000000000003349.

Holwerda, Andrew M., et al. ‘One Week of Single-Leg Immobilization Lowers Muscle Connective Protein Synthesis Rates in Healthy, Young Adults’. Medicine and Science in Sports and Exercise, vol. 56, no. 4, Nov. 2023, pp. 612–622, https://doi.org10.1249/MSS.0000000000003342.

Fuchs, Cas J., Jorn Trommelen, et al. ‘Becoming a World Champion Powerlifter at 71 Years of Age: It Is Never Too Late to Start Exercising’. International Journal of Sport Nutrition and Exercise Metabolism, Mar. 2024, pp. 1–9, https://doi.org10.1123/ijsnem.2023-0230.

Houben, Lisanne H. P., Milou Beelen, et al. ‘Resistance Exercise Training, a Simple Intervention to Preserve Muscle Mass and Strength in Prostate Cancer Patients on Androgen Deprivation Therapy’. International Journal of Sport Nutrition and Exercise Metabolism, vol. 34, no. 2, Dec. 2023, pp. 122–134, https://doi.org10.1123/ijsnem.2023-0075.

Fuchs, Cas J., Wesley J. H. Hermans, et al. ‘Daily Blood Flow Restriction Does Not Preserve Muscle Mass and Strength during 2 Weeks of Bed Rest’. The Journal of Physiology, Feb. 2024, https://doi.org10.1113/JP286065.

Pinckaers, Philippe J. M., Michelle E. G. Weijzen, et al. ‘The Muscle Protein Synthetic Response Following Corn Protein Ingestion Does Not Differ from Milk Protein in Healthy, Young Adults’. Amino Acids, vol. 56, no. 1, Feb. 2024, p. 8, https://doi.org10.1007/s00726-023-03377-z.

Weijer, Vera C. R., et al. ‘Energy Requirements of Paralympic Athletes: Insights from the Doubly Labeled Water Approach’. Medicine and Science in Sports and Exercise, Jan. 2024, https://doi.org10.1249/MSS.0000000000003379.

Betz, Milan W., et al. ‘Type II Muscle Fiber Capillarization Is an Important Determinant of Post-Exercise Microvascular Perfusion in Older Adults’. Gerontology, vol. 70, no. 3, Dec. 2023, pp. 290–301, https://doi.org10.1159/000535831.

Hilkens, Luuk, et al. ‘Jumping Exercise Combined With Collagen Supplementation Preserves Bone Mineral Density in Elite Cyclists’. International Journal of Sport Nutrition and Exercise Metabolism, vol. 34, no. 1, Oct. 2023, pp. 38–47, https://doi.org10.1123/ijsnem.2023-0080.

Marzuca-Nassr, Gabriel Nasri, et al. ‘Muscle Mass and Strength Gains Following Resistance Exercise Training in Older Adults 65-75 Years and Older Adults Above 85 Years’. International Journal of Sport Nutrition and Exercise Metabolism, vol. 34, no. 1, Oct. 2023, pp. 11–19, https://doi.org10.1123/ijsnem.2023-0087.

2023

Petrick HL, Handy RM, Vachon B, Frangos SM, Holwerda AM, Gijsen AP, Senden JM, van Loon LJC, Holloway GP. Dietary nitrate preserves mitochondrial bioenergetics and mitochondrial protein synthesis rates during short‐term immobilization in mice. J Physiol. 2023 (in press) https://www.ncbi.nlm.nih.gov/pubmed/37293995 [IF: 6.436].

Overkamp M, Houben LHP, Aussieker T, van Kranenburg JMX, Pinckaers PJM, Mikkelsen UR, Beelen M, Beijer S, van Loon LJC, Snijders T. Resistance Exercise Counteracts the Impact of Androgen Deprivation Therapy on Muscle Characteristics in Cancer Patients. J Clin Endocrinol Metab. 2023;108(10):e907‐e15 https://www.ncbi.nlm.nih.gov/pubmed/37161470 [IF: 6.134].

2022

Chapple LS, Kouw IWK, Summers MJ, Weinel LM, Gluck S, Raith E, Slobodian P, Soenen S, Deane AM, van Loon LJC, Chapman MJ. Muscle Protein Synthesis Following Protein Administration in Critical Illness. Am J Respir Crit Care Med. (in press) https://www.ncbi.nlm.nih.gov/pubmed 35584344 [IF: 21.4].

Holwerda AM, van Loon LJC. The impact of collagen protein ingestion on musculoskeletal connective tissue remodeling: a narrative review. Nutr Rev. 2022;80(6):1497‐514 https://www.ncbi.nlm.nih.gov/pubmed/34605901 [IF: 9.121].

Pasmans K, Meex RCR, van Loon LJC, Blaak EE. Nutritional strategies to attenuate postprandial glycemic response. Obes Rev. (in press):e13486 https://www.ncbi.nlm.nih.gov/pubmed/35686720 [IF: 8.483].

Bland KA, Kouw IWK, van Loon LJC, Zopf EM, Fairman CM. Exercise‐Based Interventions to Counteract Skeletal Muscle Mass Loss in People with Cancer: Can We Overcome the Odds? Sports Med. 2022;52(5):1009‐27 https://www.ncbi.nlm.nih.gov/pubmed/35118634 [IF: 7.622].

Domic J, Grootswagers P, van Loon LJC, de Groot L. Perspective: Vegan Diets for Older Adults? A Perspective On the Potential Impact On Muscle Mass and Strength. Adv Nutr. 2022;13(3):712‐25 https://www.ncbi.nlm.nih.gov/pubmed/35108354 [IF: 6.853].

Gaulton N, Wakelin G, Young LV, Wotherspoon S, Kamal M, Parise G, Nederveen JP, Holwerda A, Verdijk LB, van Loon LJC, Snijders T, Johnston AP. Twist2‐expressing cells reside in human skeletal muscle and are responsive to aging and resistance exercise training. The FASEB Journal. 2022;36(12):e22642 https://doi.org/10.1096/fj.202201349RR [IF: 5.834].

Pinckaers PJM, Hendriks FK, Hermans WJH, Goessens JPB, Senden JM, van Kranenburg JMX, Wodzig W, Snijders T, van Loon LJC. Potato Protein Ingestion Increases Muscle Protein Synthesis Rates at Rest and during Recovery from Exercise in Humans. Med Sci Sports Exerc. (in press) https://www.ncbi.nlm.nih.gov/pubmed/35438672 [IF: 5.222].

Langer HT, West D, Senden J, Spuler S, van Loon LJC, Baar K. Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling. Sci Rep. 2022;12(1):7553 https://www.ncbi.nlm.nih.gov/pubmed/35534615 [IF: 4.847].

Weijzen MEG, van Gassel RJJ, Kouw IWK, Trommelen J, Gorissen SHM, van Kranenburg J, Goessens JPB, van de Poll MCG, Verdijk LB, van Loon LJC. Ingestion of Free Amino Acids Compared with an Equivalent Amount of Intact Protein Results in More Rapid Amino Acid Absorption and
Greater Postprandial Plasma Amino Acid Availability Without Affecting Muscle Protein Synthesis Rates in Young Adults in a Double‐Blind Randomized Trial. J Nutr. 2022;152(1):59‐67 https://www.ncbi.nlm.nih.gov/pubmed/34642762 [IF: 4.423].

Hermans WJH, Fuchs CJ, Hendriks FK, Houben LHP, Senden JM, Verdijk LB, van Loon LJC. Cheese Ingestion Increases Muscle Protein Synthesis Rates Both at Rest and During Recovery from Exercise in Healthy, Young Males: A Randomized Parallel‐Group Trial. J Nutr. 2022;152(4):1022‐30 https://www.ncbi.nlm.nih.gov/pubmed/35020907 [IF: 4.423].

Fuchs CJ, Hermans WJH, Smeets JSJ, Senden JM, van Kranenburg J, Gorissen SHM, Burd NA, Verdijk LB, van Loon LJC. Raw Eggs to Support Post‐Exercise Recovery in Healthy Young Men: Did Rocky Get It Right or Wrong? J Nutr. 2022;152(11):2376‐86 https://www.ncbi.nlm.nih.gov/pubmed/35945651 [IF: 4.423].

Petrick HL, Brownell S, Vachon B, Brunetta HS, Handy RM, van Loon LJC, Murrant CL, Holloway GP. Dietary nitrate increases submaximal SERCA activity and ADP‐transfer to mitochondria in slow‐twitch muscle of female mice. Am J Physiol Endocrinol Metab. 2022;323(2):E171‐84 https://www.ncbi.nlm.nih.gov/pubmed/35732003 [IF: 4.248].

Groenendijk I, van Delft M, Versloot P, van Loon LJC, de Groot L. Impact of magnesium on bone health in older adults: A systematic review and meta‐analysis. Bone. 2022;154:116233 https://www.ncbi.nlm.nih.gov/pubmed/34666201 [IF: 4.147].

Hengist A, Davies RG, Rogers PJ, Brunstrom JM, van Loon LJC, Walhin JP, Thompson D, Koumanov F, Betts JA, Gonzalez JT. Restricting sugar or carbohydrate intake does not impact physical activity level or energy intake over 24 h despite changes in substrate use: a randomisedcrossover study in healthy men and women. Eur J Nutr. 2022https://www.ncbi.nlm.nih.gov/pubmed/36326863 [IF: 3.937].

Grootswagers P, Vaes AMM, Hangelbroek R, Tieland M, van Loon LJC, de Groot L. Relative Validity and Reliability of Isometric Lower Extremity Strength Assessment in Older Adults by Using a Handheld Dynamometer. Sports Health. 2022:19417381211063847 https://www.ncbi.nlm.nih.gov/pubmed/35120409 [IF: 3.843].

Pasmans K, Meex RCR, Trommelen J, Senden JMG, Vaughan EE, van Loon LJC, Blaak EE. L‐arabinose co‐ingestion delays glucose absorption derived from sucrose in healthy men and women: a double‐blind, randomised crossover trial. Br J Nutr. 2022;128(6):1072‐81 https://www.ncbi.nlm.nih.gov/pubmed/34657640 [IF: 3.784].

Stevens S, Hendrickx P, Snijders T, Lambrichts I, Stessel B, Dubois J, van Loon LJC, Vandenabeele F, Agten A. Skeletal Muscles of Patients Infected with SARS‐CoV‐2 Develop Severe Myofiber Damage upon One Week of Admission on the Intensive Care Unit. Applied Sciences. 2022;12(14) https://www.mdpi.com/2076-3417/12/14/7310 [IF: 2.679].

Bland KA, Krishnasamy M, Parr EB, Mulder S, Martin P, van Loon LJC, Cormie P, Michael N, Zopf EM. “I want to get myself as fit as I can and not die just yet” ‐ Perceptions of exercise in people with advanced cancer and cachexia: a qualitative study. BMC Palliat Care. 2022;21(1):75 https://www.ncbi.nlm.nih.gov/pubmed/35578224 [IF: 2.96].

Stevens S, Agten A, Snijders T, Plazier M, Bamps S, Assieker T, Betz MW, Timmermans A, van Loon LJC, Vandenabeele F. Skeletal Muscle Fibre Characteristics of the Lumbar Multifidus Muscle in Patients Undergoing Microdiscectomy for Unilateral Lumbar Disc Herniation. Muscle Ligaments and Tendons Journal. 2022;12(03) http://www.mltj.online/skeletal-muscle-fibre-characteristics-of-the-lumbar-multifidus-muscle-in-patients-undergoing-microdiscectomy-for-unilateral-lumbar-disc-herniation/ [IF: 1.142].

2021

Smeets JSJ, Horstman AMH, van Dijk DPJ, van Boxtel AGM, Ter Woorst JF, Damink S, Schijns O, van Loon LJC. Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle. J Cachexia Sarcopenia Muscle. 2021;12(3):769‐78 https://www.ncbi.nlm.nih.gov/pubmed/33951313 [IF: 7.894].

Oikawa SY, Brisbois TD, van Loon LJC, Rollo I. Eat like an athlete: insights of sports nutrition science to support active aging in healthy older adults. Geroscience. 2021;43(5):2485‐95 https://www.ncbi.nlm.nih.gov/pubmed/34283389 [IF: 7.673 ].

Rollo I, Gonzalez JT, Fuchs CJ, van Loon LJC, Williams C. Correction to: Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise. Sports Med. 2021;51(12):2671 https://www.ncbi.nlm.nih.gov/pubmed/34043186 [IF: 7.622].

Pinckaers PJM, Trommelen J, Snijders T, van Loon LJC. The Anabolic Response to Plant‐Based Protein Ingestion. Sports Med. 2021;51(Suppl 1):59‐74 https://www.ncbi.nlm.nih.gov/pubmed/34515966 [IF: 7.622].

Trommelen J, Holwerda AM, Pinckaers PJM, van Loon LJC. Comprehensive assessment of post‐prandial protein handling by the application of intrinsically labelled protein in vivo in human subjects. Proc Nutr Soc. 2021;80(2):221‐9 https://www.ncbi.nlm.nih.gov/pubmed/33487181 [IF:7.506].

Murphy CH, Flanagan EM, De Vito G, Susta D, Mitchelson KAJ, de Marco Castro E, Senden JMG, Goessens JPB, Miklosz A, Chabowski A, Segurado R, Corish CA, McCarthy SN, Egan B, van Loon LJC, Roche HM. Does supplementation with leucine‐enriched protein alone and in combination with fish‐oil‐derived n‐3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well‐nourished older adults? A randomized, double‐blind, placebo‐controlled trial. Am J Clin Nutr. 2021;113(6):1411‐27 https://www.ncbi.nlm.nih.gov/pubmed/33871558 [IF: 7.506].

Kilroe SP, Fulford J, Jackman S, Holwerda A, Gijsen A, van Loon LJC, Wall BT. Dietary protein intake does not modulate daily myofibrillar protein synthesis rates or loss of muscle mass and function during short‐term immobilization in young men: a randomized controlled trial. Am J Clin Nutr. 2021;113(3):548‐61 https://www.ncbi.nlm.nih.gov/pubmed/32469388 [IF: 7.506].

Hendriks FK, Smeets JSJ, van Kranenburg JMX, Broers NJH, van der Sande FM, Verdijk LB, Kooman JP, van Loon LJC. Amino acid removal during hemodialysis can be compensated for by protein ingestion and is not compromised by intradialytic exercise: a randomized controlled crossover trial. Am J Clin Nutr. 2021;114(6):2074‐83 https://dx.doi.org/10.1093/ajcn/nqab274 [IF:7.506].

Hermans WJH, Senden JM, Churchward‐Venne TA, Paulussen KJM, Fuchs CJ, Smeets JSJ, van Loon JJA, Verdijk LB, van Loon LJC. Insects are a viable protein source for human consumption: from insect protein digestion to postprandial muscle protein synthesis in vivo in humans: a double‐blind
randomized trial. Am J Clin Nutr. 2021;114(3):934‐44 https://www.ncbi.nlm.nih.gov/pubmed/34020450 [IF: 7.506].

Trommelen J, van Loon LJC. Assessing the whole‐body protein synthetic response to feeding in vivo in human subjects. Proc Nutr Soc. 2021;80(2):139‐47 https://www.ncbi.nlm.nih.gov/pubmed/33399528 [IF: 5.017].

Mobasheri A, Mahmoudian A, Kalvaityte U, Uzieliene I, Larder CE, Iskandar MM, Kubow S, Hamdan PC, de Almeida CS, Jr., Favazzo LJ, van Loon LJC, Emans PJ, Plapler PG, Zuscik MJ. A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis? Curr Rheumatol Rep. 2021;23(11):78 https://www.ncbi.nlm.nih.gov/pubmed/34716494 [IF: 4.592].

van der Avoort CMT, Ten Haaf DSM, Bongers C, van Oorschot F, Verdijk LB, van Loon LJC, Hopman MTE. Increasing Nitrate‐Rich Vegetable Intake Lowers Ambulatory Blood Pressure in (pre)Hypertensive Middle‐Aged and Older Adults: A 12‐Wk Randomized Controlled Trial. J Nutr. 2021;151(9):2667‐79 https://www.ncbi.nlm.nih.gov/pubmed/34236392 [IF: 4.423].

Hendriks FK, Kooman JP, van Loon LJC. Dietary protein interventions to improve nutritional status in end‐stage renal disease patients undergoing hemodialysis. Curr Opin Clin Nutr Metab Care. 2021;24(1):79‐87 https://www.ncbi.nlm.nih.gov/pubmed/33060457 [IF: 4.009].

Pinckaers PJM, Kouw IWK, Hendriks FK, van Kranenburg JMX, de Groot L, Verdijk LB, Snijders T, van Loon LJC. No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males. Br J Nutr. 2021;126(12):1832‐42 https://www.ncbi.nlm.nih.gov/pubmed/33597056 [IF: 3.784].

Kouw IWK, Pinckaers PJM, Le Bourgot C, van Kranenburg JMX, Zorenc AH, de Groot L, Verdijk L, Snijders T, van Loon LJC. Ingestion of an ample amount of meat substitute based on a lysine‐enriched, plant‐based protein blend stimulates postprandial muscle protein synthesis to a similar extent as an isonitrogenous amount of chicken in healthy, young men. Br J Nutr. 2021:1‐11 https://www.ncbi.nlm.nih.gov/pubmed/34881688 [IF: 3.784].

Snijders T, Holwerda AM, van Loon LJC, Verdijk LB. Myonuclear content and domain size in small versus larger muscle fibres in response to 12 weeks of resistance exercise training in older adults. Acta Physiol (Oxf). 2021;231(4):e13599 https://www.ncbi.nlm.nih.gov/pubmed/33314750[IF: 3.695].

Pasmans K, Adriaens ME, Olinga P, Langen R, Rensen SS, Schaap FG, Olde Damink SWM, Caiment F, van Loon LJC, Blaak EE, Meex RCR. Hepatic Steatosis Contributes to the Development of Muscle Atrophy via Inter‐Organ Crosstalk. Front Endocrinol (Lausanne). 2021;12:733625 https://www.ncbi.nlm.nih.gov/pubmed/34707570 [IF: 3.675].

Hilkens L, Knuiman P, Heijboer M, Kempers R, Jeukendrup AE, van Loon LJC, van Dijk JW. Fragile bones of elite cyclists: to treat or not to treat? J Appl Physiol (1985). 2021;131(1):26‐8 https://www.ncbi.nlm.nih.gov/pubmed/33703944 [IF: 3.519].

Hilkens L, Knuiman P, Heijboer M, Kempers R, Jeukendrup AE, van Loon LJC, van Dijk JW. Last Word on Viewpoint: Fragile bones of elite cyclists: to treat or not to treat? J Appl Physiol (1985). 2021;131(1):34‐5 https://www.ncbi.nlm.nih.gov/pubmed/34181488 [IF: 3.519].

Betz MW, Aussieker T, Kruger CQ, Gorissen SHM, van Loon LJC, Snijders T. Muscle fiber capillarization is associated with various indices of skeletal muscle mass in healthy, older men. Exp Gerontol. 2021;143:111161 https://www.ncbi.nlm.nih.gov/pubmed/33227401 [IF: 3.491].

Jonvik KL, Hoogervorst D, Peelen HB, de Niet M, Verdijk LB, van Loon LJC, van Dijk JW. The impact of beetroot juice supplementation on muscular endurance, maximal strength and countermovement jump performance. Eur J Sport Sci. 2021;21(6):871‐8 https://www.ncbi.nlm.nih.gov/pubmed/32594854 [IF: 3.228].

Hilkens L, De Bock J, Kretzers J, Kardinaal AFM, Floris‐Vollenbroek EG, Scholtens PAMJ, Horstman AMH, van Loon LJC, van Dijk JW. Whey protein supplementation does not accelerate recovery from a single bout of eccentric exercise. J Sports Sci. 2021;39(3):322‐31 https://doi.org/10.1080/02640414.2020.1820184 [IF: 3.043].

Duiven E, van Loon LJC, Spruijt L, Koert W, de Hon OM. Undeclared Doping Substances are Highly Prevalent in Commercial Sports Nutrition Supplements. J Sports Sci. 2021;20:328‐38 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219275/ [IF: 3.043].

van der Avoort CMT, Ten Haaf DSM, de Vries JHM, Verdijk LB, van Loon LJC, Eijsvogels TMH, Hopman MTE. Higher Levels of Physical Activity Are Associated with Greater Fruit and Vegetable intake in Older Adults. J Nutr Health Aging. 2021;25(2):230‐41 https://www.ncbi.nlm.nih.gov/pubmed/33491039 [IF: 2.935].

van der Avoort CMT, van Loon LJC, Verdijk LB, Poyck PPC, Thijssen DTJ, Hopman MTE. Acute Effects of Dietary Nitrate on Exercise Tolerance, Muscle Oxygenation, and Cardiovascular Function in Patients With Peripheral Arterial Disease. Int J Sport Nutr Exerc Metab. 2021;31(5):385‐96 https://www.ncbi.nlm.nih.gov/pubmed/34284348 [IF: 2.367].

Shad BJ, Thompson JL, McKendry J, Holwerda AM, Elhassan YS, Breen L, van Loon LJC, Wallis GA. Daily Myofibrillar Protein Synthesis Rates in Response to Low‐ and High‐Frequency Resistance Exercise Training in Healthy, Young Men. Int J Sport Nutr Exerc Metab. 2021;31(3):209‐16 https://www.ncbi.nlm.nih.gov/pubmed/33601335 [IF: 2.367].

Holwerda AM, Trommelen J, Kouw IWK, Senden JM, Goessens JPB, van Kranenburg J, Gijsen AP, Verdijk LB, van Loon LJC. Exercise Plus Presleep Protein Ingestion Increases Overnight Muscle Connective Tissue Protein Synthesis Rates in Healthy Older Men. Int J Sport Nutr Exerc Metab. 2021;31(3):217‐26 https://www.ncbi.nlm.nih.gov/pubmed/33588378 [IF: 2.367].

Trommelen J, Tomé D, van Loon LJC. Gut amino acid absorption in humans: concepts and relevance for postprandial metabolism. Clin Nutr Open Science. 2021;36:43‐55 https://www.sciencedirect.com/science/article/pii/S2667268521000139 [IF:

Cao J, Balluff B, Arts M, Dubois LJ, van Loon LJC, Hackeng TM, van Eijk HMH, Eijkel G, Heij LR, Soons Z, Olde Damink SWM, Heeren RMA. Mass spectrometry imaging of L‐[ring‐(13)C6]‐labeled phenylalanine and tyrosine kinetics in non‐small cell lung carcinoma. Cancer Metab. 2021;9(1):26 https://www.ncbi.nlm.nih.gov/pubmed/34116702

2020

Rollo I, Gonzalez JT, Fuchs CJ, van Loon LJC, Williams C. Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise. Sports Med. 2020;50(11):1863-71. https://link.springer.com/article/10.1007/s40279-020-01343-3 [IF:7.662].

Churchward-Venne TA, Pinckaers PJM, Smeets JSJ, Betz MW, Senden JM, Goessens JPB, Gijsen AP, Rollo I, Verdijk LB, van Loon LJC. Dose-response effects of dietary protein on muscle protein synthesis during recovery from endurance exercise in young men: a double-blind randomized trial. Am J Clin Nutr. 2020;112(2):303-17. https://www.ncbi.nlm.nih.gov/pubmed/32359142 [IF:7.506].

Nyakayiru J, van Loon LJC, Verdijk LB. Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review. Free Radic Biol Med. 2020;152:295-300. http://www.sciencedirect.com/science/article/piiS0891584919314182 [IF:6.401].

Constantin-Teodosiu D, Constantin D, Pelsers MM, Verdijk LB, van Loon LJC, Greenhaff PL. Mitochondrial DNA copy number associates with insulin sensitivity and aerobic capacity, and differs between sedentary, overweight middle-aged males with and without type 2 diabetes. Int J Obes (Lond). 2020;44(4):929-36. https://www.ncbi.nlm.nih.gov/pubmed/31641211 [IF:5.554].

Verboven K, Wens I, Vandenabeele F, Stevens A, Celie B, Lapauw B, Dendale P, van Loon LJC, Calders P, Hansen D. Impact of Exercise–Nutritional State Interactions in Patients with Type 2 Diabetes. Med Sci Sports Exerc. 2020;52(3):720-8. https://www.ncbi.nlm.nih.gov/pubmed/31652237 [IF:5.222].

Kilroe SP, Fulford J, Jackman SR, van Loon LJC, Wall BT. Temporal Muscle-Specific Disuse Atrophy during One Week of Leg Immobilization. Med Sci Sports Exerc. 2020;52(4):944-54. https://www.ncbi.nlm.nih.gov/pubmed/31688656 [IF:5.222].

Trommelen J, Holwerda AM, Senden JM, Goessens JPB, van Kranenburg J, Gijsen AP, Verdijk LB, van Loon LJC. Casein Ingestion Does Not Increase Muscle Connective Tissue Protein Synthesis Rates. Med Sci Sports Exerc. 2020;52(9):1983–91. https://www.ncbi.nlm.nih.gov/pubmed/32195768 [IF:5.222].

van der Avoort CMT, Jonvik KL, Nyakayiru J, van Loon LJC, Hopman MTE, Verdijk LB. A Nitrate-Rich Vegetable Intervention Elevates Plasma Nitrate and Nitrite Concentrations and Reduces Blood Pressure in Healthy Young Adults. J Acad Nutr Diet. 2020;120(8):1305-17. [IF:4.924]. https://doi.org/10.1016/j.jand.2020.02.014 [IF:4.924].

Dirks ML, Miotto PM, Goossens GH, Senden JM, Petrick HL, van Kranenburg J, van Loon LJC, Holloway GP. Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2O2 emission. J Physiol. 2020;598(1):123-37. https://physoc.onlinelibrary.wiley.com/doi/abs/10.1113/JP278920 [IF:4.898].

Fuchs CJ, Kouw IWK, Churchward-Venne TA, Smeets JSJ, Senden JM, Lichtenbelt W, Verdijk LB, van Loon LJC. Postexercise cooling impairs muscle protein synthesis rates in recreational athletes. J Physiol. 2020;598(4):755-72. https://www.ncbi.nlm.nih.gov/pubmed/31788800 [IF:4.898].

Petrick HL, Brunetta HS, Pignanelli C, Nunes EA, van Loon LJC, Burr JF, Holloway GP. In vitro ketone-supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle. J Physiol. 2020 598(21):4869–85. https://www.ncbi.nlm.nih.gov/pubmed/32735362 [IF:4.898].

Gorissen SHM, Trommelen J, Kouw IWK, Holwerda AM, Pennings B, Groen BBL, Wall BT, Churchward-Venne TA, Horstman AMH, Koopman R, Burd NA, Fuchs CJ, Dirks ML, Res PT, Senden JMG, Steijns J, de Groot L, Verdijk LB, van Loon LJC. Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans. J Nutr. 2020;150(8):2041-50. https://www.ncbi.nlm.nih.gov/pubmed/32069356 [IF:4.423].

Hendriks FK, Smeets JSJ, Broers NJH, van Kranenburg JMX, van der Sande FM, Kooman JP, van Loon LJC. End-Stage Renal Disease Patients Lose a Substantial Amount of Amino Acids during Hemodialysis. J Nutr. 2020;150(5):1160-6. https://www.ncbi.nlm.nih.gov/pubmed/32006029 [IF:4.423].

Tsintzas K, Jones R, Pabla P, Mallinson J, Barrett DA, Kim DH, Cooper S, Davies A, Taylor T, Gaffney C, Chee C, van Loon LJC, Stephens FB. Effect of acute and short-term dietary fat ingestion on postprandial skeletal muscle protein synthesis rates in middle-aged, overweight and obese men. Am J Physiol Endocrinol Metab. 2020;318(3):E417-E29. https://www.ncbi.nlm.nih.gov/pubmed/31910028 [IF:4.248].

Kilroe SP, Fulford J, Holwerda AM, Jackman SR, Lee BP, Gijsen AP, van Loon LJC, Wall BT. Short-term muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates. Am J Physiol Endocrinol Metab. 2020;318(2):E117-E30. https://www.ncbi.nlm.nih.gov/pubmed/31743039 [IF:4.248].

Trommelen J, Weijzen MEG, van Kranenburg J, Ganzevles RA, Beelen M, Verdijk LB, van Loon LJC. Casein Protein Processing Strongly Modulates Post-Prandial Plasma Amino Acid Responses In Vivo in Humans. Nutrients. 2020;12(8):E2299. https://www.ncbi.nlm.nih.gov/pubmed/32751788 [IF:4.187].

Geiker NRW, Mølgaard C, Iuliano S, Rizzoli R, Manios Y, van Loon LJC, Lecerf J-M, Moschonis G, Reginster J-Y, Givens I, Astrup A. Impact of whole dairy matrix on musculoskeletal health and aging–current knowledge and research gaps. Osteoporos Int. 2020;31(4):601-15. https://doi.org/10.1007/s00198-019-05229-7 [IF:3.906].

Geiker NRW, Molgaard C, Iuliano S, Rizzoli R, Manios Y, van Loon LJC, Lecerf JM, Moschonis G, Reginster JY, Givens I, Astrup A. Correction to: Impact of whole dairy matrix on musculoskeletal health and aging-current knowledge and research gaps. Osteoporos Int. 2020;31(4):795. https://www.ncbi.nlm.nih.gov/pubmed/31932961 [IF:3.906].

Nyakayiru J, van Lieshout GAA, Trommelen J, van Kranenburg J, Verdijk LB, Bragt MCE, van Loon LJC. The glycation level of milk protein strongly modulates post-prandial lysine availability in humans. Br J Nutr. 2020;123(5):545-52. https://www.ncbi.nlm.nih.gov/pubmed/31727194 [IF:3.784].

Snijders T, Aussieker T, Holwerda A, Parise G, van Loon L, Verdijk LB. The concept of skeletal muscle memory: evidence from animal and human studies. Acta Physiol (Oxf). 2020;229(3):e13465. https://www.ncbi.nlm.nih.gov/pubmed/32175681 [IF:3.695].

Fuchs CJ, Smeets JSJ, Senden JM, Zorenc AH, Goessens JPB, van Marken Lichtenbelt WD, Verdijk LB, van Loon LJC. Hot-water immersion does not increase post-prandial muscle protein synthesis rates during recovery from resistance-type exercise in healthy, young males. J Appl Physiol (1985). 2020;128(4):1012-22. https://www.ncbi.nlm.nih.gov/pubmed/32191599 [IF:3.519].

Weijzen MEG, Kouw IWK, Geerlings P, Verdijk LB, van Loon LJC. During Hospitalization, Older Patients at Risk for Malnutrition Consume <0.65 Grams of Protein per Kilogram Body Weight per Day. Nutr Clin Pract. 2020;35(4):655–63. https://onlinelibrary.wiley.com/doi/full/10.1002/ncp.10542 [IF:2.765].

Gonzalez JT, Dirks ML, Holwerda AM, Kouw IWK, van Loon LJC. Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest. Eur J Appl Physiol. 2020;120(9):2083-94. https://doi.org/10.1007/s00421-020-04431-4 [IF:2.567].

Betts JA, Gonzalez JT, Burke LM, Close GL, Garthe I, James LJ, Jeukendrup AE, Morton JP, Nieman DC, Peeling P, Phillips SM, Stellingwerff T, van Loon LJC, Williams C, Woolf K, Maughan R, Atkinson G. PRESENT 2020: Text Expanding on the Checklist for Proper Reporting of Evidence in Sport and Exercise Nutrition Trials. Int J Sport Nutr Exerc Metab. 2020;30(1):2-13. https://www.ncbi.nlm.nih.gov/pubmed/31945740 [IF:2.367].

Holwerda AM, Bouwman FG, Nabben M, Wang P, van Kranenburg J, Gijsen AP, Burniston JG, Mariman ECM, van Loon LJC. Endurance-Type Exercise Increases Bulk and Individual Mitochondrial Protein Synthesis Rates in Rats. Int J Sport Nutr Exerc Metab. 2020;30(2):153-64. https://www.ncbi.nlm.nih.gov/pubmed/32035417 [IF:2.367].

Sipers WMWH, Dorge J, Schols JMGA, Verdijk LB, van Loon LJC. Multifrequency bioelectrical impedance analysis may represent a reproducible and practical tool to assess skeletal muscle mass in euvolemic acutely ill hospitalized geriatric patients. Eur Geriatr Med. 2020;11:155-62. https://doi.org/10.1007/s41999-019-00253-6 [IF:1.284].

Brunetta HS, Holwerda AM, van Loon LJC, Holloway GP. Mitochondrial ROS and Aging: Understanding Exercise as a Preventive Tool. Journal of Science in Sport and Exercise. 2020;2:15–24. https://link.springer.com/article/10.1007/s42978-019-00037-1#enumeration.

Betts JA, Gonzalez JT, Burke LM, Close GL, Garthe I, James LJ, Jeukendrup AE, Morton JP, Nieman DC, Peeling P, Phillips SM, Stellingwerff T, van Loon LJC, Williams C, Woolf K, Maughan R, Atkinson G. PRESENT 2020: Texto que desarrolla la lista de verificación para el adecuado informe de la evidencia en ensayos clínicos de deporte y nutrición del ejercicio (Traducción Inglés-Español). Rev Andal Med Deporte. 2020;13(4):244-54. [IF:0.38].https://ws072.juntadeandalucia.es/ojs/index.php/ramd/article/view/875

2019

Meex RCR, Blaak EE, van Loon LJC. Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes. Obes Rev. 2019;20(9):1205-17.https://www.ncbi.nlm.nih.gov/pubmed/31240819 [IF:8.483].

van Dijk DPJ, Horstman AMH, Smeets JSJ, den Dulk M, Grabsch HI, Dejong CHC, Rensen SS, Olde Damink SWM, van Loon LJC. Tumour-specific and organ-specific protein synthesis rates in patients with pancreatic cancer. J Cachexia Sarcopenia Muscle. 2019;10(3):549-56. https://www.ncbi.nlm.nih.gov/pubmed/30868736 [IF:7.894].

Kneppers AEM, Haast RAM, Langen RCJ, Verdijk LB, Leermakers PA, Gosker HR, van Loon LJC, Lainscak M, Schols A. Distinct skeletal muscle molecular responses to pulmonary rehabilitation in chronic obstructive pulmonary disease: a cluster analysis. J Cachexia Sarcopenia Muscle. 2019;10(2):311-22. https://www.ncbi.nlm.nih.gov/pubmed/30657653[IF:7.894].

Trommelen J, Betz MW, van Loon LJC. The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise. Sports Med. 2019;49(2):185–97. https://www.ncbi.nlm.nih.gov/pubmed/30659499 [IF:7.622].

Knuiman P, van Loon LJC, Wouters J, Hopman M, Mensink M. Protein supplementation elicits greater gains in maximal oxygen uptake capacity and stimulates lean mass accretion during prolonged endurance training: a double-blind randomized controlled trial. Am J Clin Nutr. 2019;110(2):508-18. https://www.ncbi.nlm.nih.gov/pubmed/31240303 [IF:7.506].

Fuchs CJ, Hermans WJH, Holwerda AM, Smeets JSJ, Senden JM, van Kranenburg J, Gijsen AP, Wodzig W, Schierbeek H, Verdijk LB, van Loon LJC. Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial. Am J Clin Nutr. 2019;110(4):862-72. https://www.ncbi.nlm.nih.gov/pubmed/31250889 [IF:7.506].

Kramer IF, Blokhuis TJ, Verdijk LB, van Loon LJC, Poeze M. Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients. Nutr Rev. 2019;77(4):254–66. https://www.ncbi.nlm.nih.gov/pubmed/30624706[IF:6.428].

Horstman AMH, Kouw IWK, van Dijk JW, Hamer HM, Groen BBL, van Kranenburg J, Gorissen SHM, van Loon LJC. The muscle protein synthetic response to whey protein ingestion is greater in middle-aged women when compared with men. J Clin Endocrinol Metab. 2019;104(4):994–1004. https://www.ncbi.nlm.nih.gov/pubmed/30423113 [IF:6.215].

Mason SA, Rasmussen B, van Loon LJC, Salmon J, Wadley GD. Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in people with type 2 diabetes: Findings of a randomized cross-over trial. Diabetes Obes Metab. 2019;21(3):674-82. https://www.ncbi.nlm.nih.gov/pubmed/30394006 [IF:5.888].

Kouw IWK, Groen BBL, Smeets JSJ, Kramer IF, van Kranenburg JMX, Nilwik R, Geurts JAP, Ten Broeke RHM, Poeze M, van Loon LJC, Verdijk LB. One Week of Hospitalization Following Elective Hip Surgery Induces Substantial Muscle Atrophy in Older Patients. J Am Med Dir Assoc. 2019;20:35-42. https://www.ncbi.nlm.nih.gov/pubmed/30108034 [IF:5.449].

Smiles WJ, Churchward-Venne TA, van Loon LJC, Hawley JA, Camera DM. A single bout of strenuous exercise overcomes lipid-induced anabolic resistance to protein ingestion in overweight, middle-aged men. FASEB J. 2019;33(6):7009-17. https://www.ncbi.nlm.nih.gov/pubmed/30840513 [IF:5.337].

Kneppers A, Leermakers P, Pansters N, Backx E, Gosker H, van Loon LJC, Schols A, Langen R, Verdijk L. Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse. FASEB J. 2019;33(1):1288-98. https://www.ncbi.nlm.nih.gov/pubmed/30133324 [IF:5.337].

Shad BJ, Thompson JL, Holwerda AM, Stocks B, Elhassan YS, Philp A, van Loon LJC, Wallis GA. One Week of Step Reduction Lowers Myofibrillar Protein Synthesis Rates in Young Men. Med Sci Sports Exerc. 2019;51(10):2125-34. https://www.ncbi.nlm.nih.gov/pubmed/31083048 [IF:5.222].

Nyakayiru J, Fuchs CJ, Trommelen J, Smeets JSJ, Senden JM, Gijsen AP, Zorenc AH, van Loon LJC, Verdijk LB. Blood Flow Restriction Only Increases Myofibrillar Protein Synthesis with Exercise. Med Sci Sports Exerc. 2019;51(6):1137-45. https://www.ncbi.nlm.nih.gov/pubmed/30694972 [IF:5.222].

Jonvik KL, Paulussen KJM, Danen SL, Ceelen IJM, Horstman AM, Wardenaar FC, van Loon LJC, van Dijk JW. Protein Supplementation Does Not Augment Adaptations to Endurance Exercise Training. Med Sci Sports Exerc. 2019;51(10):2041-9. https://www.ncbi.nlm.nih.gov/pubmed/31525168 [IF:5.222].

Jonvik KL, Lenaerts K, Smeets JSJ, Kolkman JJ, van Loon LJC, Verdijk LB. Sucrose but Not Nitrate Ingestion Reduces Strenuous Cycling–induced Intestinal Injury. Med Sci Sports Exerc. 2019;51(3):436-44. https://www.ncbi.nlm.nih.gov/pubmed/30299412 [IF:5.222].

Petrick HL, Pignanelli C, Barbeau PA, Churchward-Venne TA, Dennis K, van Loon LJC, Burr JF, Goossens GH, Holloway GP. Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2 O2 emission rates in human skeletal muscle. J Physiol. 2019;597(15):3985-97. https://www.ncbi.nlm.nih.gov/pubmed/31194254 [IF:4.898].

Fuchs CJ, Gonzalez JT, van Loon LJC. Fructose co-ingestion to increase carbohydrate availability in athletes. J Physiol. 2019;597(14):3549-60. https://www.ncbi.nlm.nih.gov/pubmed/31166604 [IF:4.898].

Groenendijk I, den Boeft L, van Loon LJC, de Groot LCPM. High versus low dietary protein intake and bone health in older adults: A systematic review and meta-analysis. Computational and Structural Biotechnology Journal. 2019;17:1101–12. http://www.sciencedirect.com/science/article/pii/S2001037019301448 [IF:4.720].

Kouw IWK, van Dijk JW, Horstman AMH, Kramer IF, Goessens JPB, van Dielen FMH, Verdijk LB, van Loon LJC. Basal and Postprandial Myofibrillar Protein Synthesis Rates Do Not Differ between Lean and Obese Middle-Aged Men. J Nutr. 2019;149(9):1533–42. https://www.ncbi.nlm.nih.gov/pubmed/31174213 [IF:4.423].

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig W, Verdijk LB, van Loon LJC. Dose-Dependent Increases in Whole-Body Net Protein Balance and Dietary Protein-Derived Amino Acid Incorporation into Myofibrillar Protein During Recovery from Resistance Exercise in Older Men. J Nutr. 2019;149(2):221–30. https://www.ncbi.nlm.nih.gov/pubmed/30722014 [IF:4.423].

Churchward-Venne TA, Pinckaers PJM, Smeets JSJ, Peeters WM, Zorenc AH, Schierbeek H, Rollo I, Verdijk LB, van Loon LJC. Myofibrillar and Mitochondrial Protein Synthesis Rates Do Not Differ in Young Men Following the Ingestion of Carbohydrate with Milk Protein, Whey, or Micellar Casein after Concurrent Resistance- and Endurance-Type Exercise. J Nutr. 2019;149(2):198–209. https://www.ncbi.nlm.nih.gov/pubmed/30698725 [IF:4.423].

Churchward-Venne TA, Pinckaers PJM, Smeets JSJ, Peeters WM, Zorenc AH, Schierbeek H, Rollo I, Verdijk LB, van Loon LJC. Myofibrillar and Mitochondrial Protein Synthesis Rates Do Not Differ in Young Men Following the Ingestion of Carbohydrate with Whey, Soy, or Leucine-Enriched Soy Protein after Concurrent Resistance- and Endurance-Type Exercise. J Nutr. 2019;149(2):210–20. https://www.ncbi.nlm.nih.gov/pubmed/30698812 [IF:4.423].

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig W, Verdijk LB, de Groot L, van Loon LJC. Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men. Am J Physiol Endocrinol Metab. 2019;317(3):E473-E82. https://www.ncbi.nlm.nih.gov/pubmed/31112406 [IF:4.248].

Dirks ML, Smeets JSJ, Holwerda AM, Kouw IWK, Marzuca-Nassr GN, Gijsen AP, Holloway GP, Verdijk LB, van Loon LJC. Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest. Am J Physiol Endocrinol Metab. 2019;316(3):E536-E45. https://www.ncbi.nlm.nih.gov/pubmed/30645176 [IF:4.248].

Trommelen J, Holwerda AM, Nyakayiru J, Gorissen SHM, Rooyackers O, Burd NA, Boirie Y, van Loon LJC. The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation. Am J Physiol Endocrinol Metab. 2019;317(3):E433-E4 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/31423800 [IF:4.248].

Hendriks FK, Smeets JSJ, van der Sande FM, Kooman JP, van Loon LJC. Dietary Protein and Physical Activity Interventions to Support Muscle Maintenance in End-Stage Renal Disease Patients on Hemodialysis. Nutrients. 2019;11(12):2972. https://www.mdpi.com/2072-6643/11/12/2972 [IF:4.187].

Vaes AMM, Brouwer-Brolsma EM, Toussaint N, de Regt M, Tieland M, van Loon LJC, de Groot LCPGM. The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults. Eur J Nutr. 2019;58:1173–81. https://www.ncbi.nlm.nih.gov/pubmed/29691654 [IF:3.937].

van Vliet S, Beals JW, Holwerda AM, Emmons RS, Goessens JP, Paluska SA, De Lisio M, van Loon LJC, Burd NA. Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men. J Appl Physiol (1985). 2019;127(6):1792-801. https://www.ncbi.nlm.nih.gov/pubmed/31725358 [IF:3.519].

Snijders T, Leenders M, de Groot L, van Loon LJC, Verdijk LB. Muscle mass and strength gains following 6months of resistance type exercise training are only partly preserved within one year with autonomous exercise continuation in older adults. Exp Gerontol. 2019;121:71-8. https://www.ncbi.nlm.nih.gov/pubmed/30978433 [IF:3.491].

Horstman AMH, Backx EMP, Smeets JSJ, Marzuca-Nassr GN, van Kranenburg J, de Boer D, Dolmans J, Snijders T, Verdijk LB, de Groot L, van Loon LJC. Nandrolone decanoate administration does not attenuate muscle atrophy during a short period of disuse. PLoS One. 2019;14(1):e0210823. https://www.ncbi.nlm.nih.gov/pubmed/30689637 [IF:3.394].

Smeets JSJ, Horstman AMH, Vles GF, Emans PJ, Goessens JPB, Gijsen AP, van Kranenburg JMX, van Loon LJC. Protein synthesis rates of muscle, tendon, ligament, cartilage, and bone tissue in vivo in humans. PLoS One. 2019;14(11):e0224745. https://www.ncbi.nlm.nih.gov/pubmed/31697717 [IF:3.394].

Brinkmans NYJ, Iedema N, Plasqui G, Wouters L, Saris WHM, van Loon LJC, van Dijk JW. Energy expenditure and dietary intake in professional football players in the Dutch Premier League: Implications for nutritional counselling. J Sports Sci. 2019;37(24):2759-67. https://www.ncbi.nlm.nih.gov/pubmed/30773995 [IF:3.043].

Boujemaa H, Yilmaz A, Robic B, Koppo K, Claessen G, Frederix I, Dendale P, Voller H, van Loon LJC, Hansen D. The effect of minimally invasive surgical aortic valve replacement on postoperative pulmonary and skeletal muscle function. Exp Physiol. 2019;104(6):855-65. https://www.ncbi.nlm.nih.gov/pubmed/30938881 [IF:2.937].

Weijzen MEG, Kouw IWK, Verschuren AAJ, Muyters R, Geurts JA, Emans PJ, Geerlings P, Verdijk LB, van Loon LJC. Protein Intake Falls below 0.6 g*kg-1*d-1 in Healthy, Older Patients Admitted for Elective Hip or Knee Arthroplasty. J Nutr Health Aging. 2019;23(3):299-305. https://www.ncbi.nlm.nih.gov/pubmed/30820520 [IF:2.935].

Sipers W, de Blois W, Schols J, van Loon LJC, Verdijk LB. Sarcopenia Is Related to Mortality in the Acutely Hospitalized Geriatric Patient. J Nutr Health Aging. 2019;23(2):128-37. https://www.ncbi.nlm.nih.gov/pubmed/30697621 [IF:2.935].

Hangelbroek RWJ, Vaes AMM, Boekschoten MV, Verdijk LB, Hooiveld G, van Loon LJC, de Groot LCPGM, Kersten S. No effect of 25-hydroxyvitamin D supplementation on the skeletal muscle transcriptome in vitamin D deficient frail older adults. BMC Geriatr. 2019;19(1):151. https://www.ncbi.nlm.nih.gov/pubmed/31138136 [IF:2.866].

Leermakers PA, Kneppers AEM, Schols A, Kelders M, de Theije CC, Verdijk LB, van Loon LJC, Langen RCJ, Gosker HR. Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation. Muscle Nerve. 2019;60(6):769-78. https://www.ncbi.nlm.nih.gov/pubmed/31495926 [IF:2.560].

McKenna CF, Salvador AF, Hendriks FK, Harris APY, van Loon LJC, Burd NA. Exercising to offset muscle mass loss in hemodialysis patients: The disconnect between intention and intervention. Semin Dial. 2019;32(4):379-85. https://www.ncbi.nlm.nih.gov/pubmed/30903629 [IF:1.671].

Wickham KA, McCarthy DG, Pereira JM, Cervone DT, Verdijk LB, van Loon LJC, Power GA, Spriet LL. No effect of beetroot juice supplementation on exercise economy and performance in recreationally active females despite increased torque production. Physiol Rep. 2019;7(2):e13982. https://www.ncbi.nlm.nih.gov/pubmed/30653856.

Snijders T, Trommelen J, Kouw IWK, Holwerda AM, Verdijk LB, van Loon LJC. The Impact of Pre-sleep Protein Ingestion on the Skeletal Muscle Adaptive Response to Exercise in Humans: An Update. Front Nutr. 2019;6(17). https://www.frontiersin.org/article/10.3389/fnut.2019.00017.

2018

Smeets JSJ, Horstman AMH, Schijns O, Dings JTA, Hoogland G, Gijsen AP, Goessens JPB, Bouwman FG, Wodzig W, Mariman EC, van Loon LJC. Brain tissue plasticity: protein synthesis rates of the human brain. Brain. 2018;141(4):1122-9. https://www.ncbi.nlm.nih.gov/pubmed/29432531 [IF:10.767].

Holloway GP, Holwerda AM, Miotto PM, Dirks ML, Verdijk LB, van Loon LJC. Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle. Cell Rep. 2018;22(11):2837-48. https://www.ncbi.nlm.nih.gov/pubmed/29539414 [IF:8.728 ].

Maughan RJ, Burke LM, Dvorak J, Larson-Meyer DE, Peeling P, Phillips SM, Rawson ES, Walsh NP, Garthe I, Geyer H, Meeusen R, van Loon LJC, Shirreffs SM, Spriet LL, Stuart M, Vernec A, Currell K, Ali VM, Budgett RG, Ljungqvist A, Mountjoy M, Pitsiladis YP, Soligard T, Erdener U, Engebretsen L. IOC consensus statement: dietary supplements and the high-performance athlete. Br J Sports Med. 2018;52(7):439-55. https://www.ncbi.nlm.nih.gov/pubmed/29540367[IF:6.644].

Weggemans RM, Backx FJG, Borghouts L, Chinapaw M, Hopman MTE, Koster A, Kremers S, van Loon LJC, May A, Mosterd A, van der Ploeg HP, Takken T, Visser M, Wendel-Vos GCW, de Geus EJC, Committee Dutch Physical Activity Guidelines 2017. The 2017 Dutch Physical Activity Guidelines. Int J Behav Nutr Phys Act. 2018;15(1):58. https://www.ncbi.nlm.nih.gov/pubmed/29940977 [IF:6.214].

Tomcik KA, Camera DM, Bone JL, Ross ML, Jeacocke NA, Tachtsis B, Senden J, van Loon LJC, Hawley JA, Burke LM. Effects of Creatine and Carbohydrate Loading on Cycling Time Trial Performance. Med Sci Sports Exerc. 2018;50(1):141-50. https://www.ncbi.nlm.nih.gov/pubmed/28806275 [IF:5.222].

Holloway TM, Snijders T, van Kranenburg J, van Loon LJC, Verdijk LB. Temporal Response of Angiogenesis and Hypertrophy to Resistance Training in Young Men. Med Sci Sports Exerc. 2018;50(1):36-45. https://www.ncbi.nlm.nih.gov/pubmed/28846563 [IF:5.222].

Vaes AMM, Tieland M, de Regt MF, Wittwer J, van Loon LJC, de Groot LCPGM. Dose-response effects of supplementation with calcifediol on serum 25-hydroxyvitamin D status and its metabolites: A randomized controlled trial in older adults. Clin Nutr. 2018;37(3):808-14. https://www.ncbi.nlm.nih.gov/pubmed/28433267 [IF:4.916].

Robinson SM, Reginster JY, Rizzoli R, Shaw SC, Kanis JA, Bautmans I, Bischoff-Ferrari H, Bruyere O, Cesari M, Dawson-Hughes B, Fielding RA, Kaufman JM, Landi F, Malafarina V, Rolland Y, van Loon LJC, Vellas B, Visser M, Cooper C, group Ew. Does nutrition play a role in the prevention and management of sarcopenia? Clin Nutr. 2018;37(4):1121-32. https://www.ncbi.nlm.nih.gov/pubmed/28927897 [IF:4.916].

Beijers R, Huysmans SMD, van de Bool C, Kingma BRM, Verdijk LB, van Loon LJC, Meex SJR, Gosker HR, Schols A. The effect of acute and 7-days dietary nitrate on mechanical efficiency, exercise performance and cardiac biomarkers in patients with chronic obstructive pulmonary disease. Clin Nutr. 2018;37:1852-61. https://www.ncbi.nlm.nih.gov/pubmed/29108664 [IF:4.916].

Vaes AMM, Tieland M, Toussaint N, Nilwik R, Verdijk LB, van Loon LJC, de Groot LCPGM. Cholecalciferol or 25-Hydroxycholecalciferol Supplementation Does Not Affect Muscle Strength and Physical Performance in Prefrail and Frail Older Adults. J Nutr. 2018;148(5):712-20. https://academic.oup.com/jn/article/148/5/712/4990752 [IF:4.423].

Holwerda AM, Overkamp M, Paulussen KJM, Smeets JSJ, van Kranenburg J, Backx EMP, Gijsen AP, Goessens JPB, Verdijk LB, van Loon LJC. Protein Supplementation after Exercise and before Sleep Does Not Further Augment Muscle Mass and Strength Gains during Resistance Exercise Training in Active Older Men. J Nutr. 2018;148(11):1723-32. https://www.ncbi.nlm.nih.gov/pubmed/30247714 [IF:4.423].

Kneppers A, Verdijk L, de Theije C, Corten M, Gielen E, van Loon LJC, Schols A, Langen R. A novel in vitro model for the assessment of postnatal myonuclear accretion. Skelet Muscle. 2018;8(1):4. https://www.ncbi.nlm.nih.gov/pubmed/29444710 [IF:4.361 ].

Trommelen J, Kouw IWK, Holwerda AM, Snijders T, Halson SL, Rollo I, Verdijk LB, van Loon LJC. Presleep dietary protein-derived amino acids are incorporated in myofibrillar protein during postexercise overnight recovery. Am J Physiol Endocrinol Metab. 2018;314(5):E457-E67. https://www.ncbi.nlm.nih.gov/pubmed/28536184 [IF:4.248].

Langer HT, Senden JMG, Gijsen AP, Kempa S, van Loon LJC, Spuler S. Muscle Atrophy Due to Nerve Damage Is Accompanied by Elevated Myofibrillar Protein Synthesis Rates. Front Physiol. 2018;9:1220. https://www.ncbi.nlm.nih.gov/pubmed/30233398 [IF:4.187].

Backx EMP, Horstman AMH, Marzuca-Nassr GN, van Kranenburg J, Smeets JS, Fuchs CJ, Janssen AAW, de Groot L, Snijders T, Verdijk LB, van Loon LJC. Leucine Supplementation Does Not Attenuate Skeletal Muscle Loss during Leg Immobilization in Healthy, Young Men. Nutrients. 2018;10(5):pii: E635. https://www.ncbi.nlm.nih.gov/pubmed/29772844 [IF:4.187].

Haskovic M, Derks B, van der Ploeg L, Trommelen J, Nyakayiru J, van Loon LJC, Mackinnon S, Yue WW, Peake RWA, Zha L, Demirbas D, Qi W, Huang X, Berry GT, Achten J, Bierau J, Rubio-Gozalbo ME, Coelho AI. Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia. Orphanet J Rare Dis. 2018;13(1):212. https://www.ncbi.nlm.nih.gov/pubmed/30477550 [IF:4.185 ].

Niemeijer VM, Snijders T, Verdijk LB, van Kranenburg J, Groen BBL, Holwerda AM, Spee RF, Wijn PFF, van Loon LJC, Kemps HMC. Skeletal muscle fiber characteristics in patients with chronic heart failure: impact of disease severity and relation with muscle oxygenation during exercise. J Appl Physiol (1985). 2018;125:1266–76. https://www.ncbi.nlm.nih.gov/pubmed/30091667 [IF:3.519].

Holwerda AM, Paulussen KJM, Overkamp M, Smeets JSJ, Gijsen AP, Goessens JPB, Verdijk LB, van Loon LJC. Daily resistance-type exercise stimulates muscle protein synthesis in vivo in young men. J Appl Physiol (1985). 2018;124(1):66-75. https://www.ncbi.nlm.nih.gov/pubmed/28935828 [IF:3.519].

Dirks ML, Wall BT, van Loon LJC. Interventional strategies to combat muscle disuse atrophy in humans: focus on neuromuscular electrical stimulation and dietary protein. J Appl Physiol (1985). 2018;125(3):850-61. https://www.ncbi.nlm.nih.gov/pubmed/28970205 [IF:3.519].

Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP. Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats.Am J Physiol Regul Integr Comp Physiol. 2018;315(2):R191-R204. https://www.ncbi.nlm.nih.gov/pubmed/29513565[IF:3.290].

van der Avoort CMT, van Loon LJC, Hopman MTE, Verdijk LB. Increasing vegetable intake to obtain the health promoting and ergogenic effects of dietary nitrate. Eur J Clin Nutr. 2018;72(11):1485-9. https://www.ncbi.nlm.nih.gov/pubmed/29559721 [IF:3.057].

Gorissen SHM, Crombag JJR, Senden JMG, Waterval WAH, Bierau J, Verdijk LB, van Loon LJC. Protein content and amino acid composition of commercially available plant-based protein isolates. Amino Acids. 2018;50(12):1685-95. https://www.ncbi.nlm.nih.gov/pubmed/30167963 [IF:2.946].

Dirks ML, Stephens FB, Jackman SR, Galera Gordo J, Machin DJ, Pulsford RM, van Loon LJC, Wall BT. A single day of bed rest, irrespective of energy balance, does not affect skeletal muscle gene expression or insulin sensitivity. Exp Physiol. 2018;103(6):860-75. https://www.ncbi.nlm.nih.gov/pubmed/29656554 [IF:2.937].

Maughan RJ, Burke LM, Dvorak J, Larson-Meyer DE, Peeling P, Phillips SM, Rawson ES, Walsh NP, Garthe I, Geyer H, Meeusen R, van Loon LJC, Shirreffs SM, Spriet LL, Stuart M, Vernec A, Currell K, Ali VM, Budgett RGM, Ljungqvist A, Mountjoy M, Pitsiladis Y, Soligard T, Erdener U, Engebretsen L. IOC Consensus Statement: Dietary Supplements and the High-Performance Athlete. Int J Sport Nutr Exerc Metab. 2018;28(2):104-25. https://www.ncbi.nlm.nih.gov/pubmed/29589768 [IF:2.367].

Jonvik KL, van Dijk JW, Senden JMG, van Loon LJC, Verdijk LB. The Effect of Beetroot Juice Supplementation on Dynamic Apnea and Intermittent Sprint Performance in Elite Female Water Polo Players. Int J Sport Nutr Exerc Metab. 2018;28(5):468-73. https://www.ncbi.nlm.nih.gov/pubmed/29252047 [IF:2.367].

Jonvik KL, Nyakayiru J, van Dijk JW, Maase K, Ballak SB, Senden JMG, van Loon LJC, Verdijk LB. Repeated-sprint performance and plasma responses following beetroot juice supplementation do not differ between recreational, competitive and elite sprint athletes. Eur J Sport Sci. 2018;18(4):524-33. https://www.ncbi.nlm.nih.gov/pubmed/29412076 [IF:2.323].

Hansen D, Verboven K, van Dijk JW, Zorenc A, Minten L, Smeets K, Verdijk LB, van Loon LJC. Adipose tissue lipolytic inhibition enhances the glucoregulatory properties of exercise in type 2 diabetes patients. Eur J Sport Sci. 2018;18(9):1245-54. https://www.ncbi.nlm.nih.gov/pubmed/29938604 [IF:2.323].

Dijk FJ, van Dijk M, Walrand S, van Loon LJC, van Norren K, Luiking YC. Differential effects of leucine and leucine-enriched whey protein on skeletal muscle protein synthesis in aged mice. Clin Nutr ESPEN. 2018;24:127-33. https://www.ncbi.nlm.nih.gov/pubmed/29576350.

Smeets JSJ, van Loon LJC. Reply: Measurement of regional rates of protein synthesis in human brain in vivo with L-[1-11C]-leucine PET. Brain. 2018;141(7):e52 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/29726903.

Whitfield J, Heigenhauser GJF, van Loon LJC, Spriet LL, Tupling AR, Holloway GP. Response. Med Sci Sports Exerc. 2018;50(4):875. https://www.ncbi.nlm.nih.gov/pubmed/29547496.

2017

Arts M, Soons Z, Ellis SR, Pierzchalski KA, Balluff B, Eijkel GB, Dubois LJ, Lieuwes NG, Agten SM, Hackeng TM, van Loon LJC, Heeren RMA, Olde Damink SWM. Detection of Localized Hepatocellular Amino Acid Kinetics by using Mass Spectrometry Imaging of Stable Isotopes. Angew Chem Int Ed Engl. 2017;56(25):7146-50. https://www.ncbi.nlm.nih.gov/pubmed/28493648 [IF:11.838].

Snijders T, Nederveen JP, Joanisse S, Leenders M, Verdijk LB, van Loon LJC, Parise G. Muscle fibre capillarization is a critical factor in muscle fibre hypertrophy during resistance exercise training in older men. J Cachexia Sarcopenia Muscle. 2017;8(2):267-76. https://www.ncbi.nlm.nih.gov/pubmed/27897408 [IF:7.894].

Pinckaers PJ, Churchward-Venne TA, Bailey D, van Loon LJC. Ketone Bodies and Exercise Performance: The Next Magic Bullet or Merely Hype? Sports Med. 2017;47(3):383-91. https://www.ncbi.nlm.nih.gov/pubmed/27430501 [IF:7.622].

Backx EMP, Hangelbroek R, Snijders T, Verscheijden ML, Verdijk LB, de Groot LCPGM, van Loon LJC. Creatine Loading Does Not Preserve Muscle Mass or Strength During Leg Immobilization in Healthy, Young Males: A Randomized Controlled Trial. Sports Med. 2017;47(8):1661-71. https://www.ncbi.nlm.nih.gov/pubmed/28054322 [IF:7.622].

Gorissen SH, Horstman AM, Franssen R, Kouw IW, Wall BT, Burd NA, de Groot LC, van Loon LJC. Habituation to low or high protein intake does not modulate basal or postprandial muscle protein synthesis rates: a randomized trial. Am J Clin Nutr. 2017;105(2):332-42. https://www.ncbi.nlm.nih.gov/pubmed/27903518 [IF:7.506].

Nyakayiru J, Verdijk LB, Cermak NM, van Loon LJC. Team Rwanda: will Africans dominate professional road cycling in the future? Br J Sports Med. 2017;51(10):827-8. https://www.ncbi.nlm.nih.gov/pubmed/27162234 [IF:6.644].

Churchward-Venne TA, Pinckaers PJM, van Loon JJA, van Loon LJC. Consideration of insects as a source of dietary protein for human consumption. Nutr Rev. 2017;75(12):1035-45. https://www.ncbi.nlm.nih.gov/pubmed/29202184[IF:6.428].

Kramer IF, Snijders T, Smeets JSJ, Leenders M, van Kranenburg J, den Hoed M, Verdijk LB, Poeze M, van Loon LJC. Extensive Type II Muscle Fiber Atrophy in Elderly Female Hip Fracture Patients. J Gerontol A Biol Sci Med Sci. 2017;72(10):1369-75. https://www.ncbi.nlm.nih.gov/pubmed/28329045 [IF:5.783].

Dirks ML, Tieland M, Verdijk LB, Losen M, Nilwik R, Mensink M, de Groot L, van Loon LJC. Protein Supplementation Augments Muscle Fiber Hypertrophy but Does Not Modulate Satellite Cell Content During Prolonged Resistance-Type Exercise Training in Frail Elderly. J Am Med Dir Assoc. 2017;18(7):608-15. https://www.ncbi.nlm.nih.gov/pubmed/28377156 [IF:5.449].

Whitfield J, Gamu D, Heigenhauser GJF, van Loon LJC, Spriet LL, Tupling AR, Holloway GP. Beetroot Juice Increases Human Muscle Force Without Changing Ca2+-handling Proteins. Med Sci Sports Exerc. 2017;49(10):2016-24. https://www.ncbi.nlm.nih.gov/pubmed/28509762 [IF:5.222].

Kramer IF, Verdijk LB, Hamer HM, Verlaan S, Luiking YC, Kouw IWK, Senden JM, van Kranenburg J, Gijsen AP, Bierau J, Poeze M, van Loon LJC. Both basal and post-prandial muscle protein synthesis rates, following the ingestion of a leucine-enriched whey protein supplement, are not impaired in sarcopenic older males. Clin Nutr. 2017;36(5):1440-9. https://www.ncbi.nlm.nih.gov/pubmed/27743615 [IF:4.916].

Gorissen SH, Burd NA, Kramer IF, van Kranenburg J, Gijsen AP, Rooyackers O, van Loon LJC. Co-ingesting milk fat with micellar casein does not affect postprandial protein handling in healthy older men. Clin Nutr. 2017;36(2):429-37. https://www.ncbi.nlm.nih.gov/pubmed/26774526 [IF:4.916].

Barbeau PA, Holloway TM, Whitfield J, Baechler BL, Quadrilatero J, van Loon LJC, Chabowski A, Holloway GP. alpha-Linolenic acid and exercise training independently, and additively, decrease blood pressure and prevent diastolic dysfunction in obese Zucker rats. J Physiol. 2017;595(13):4351-64. https://www.ncbi.nlm.nih.gov/pubmed/28345766[IF:4.898].

Kouw IW, Holwerda AM, Trommelen J, Kramer IF, Bastiaanse J, Halson SL, Wodzig WK, Verdijk LB, van Loon LJC. Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial. J Nutr. 2017;147(12):2252-61. https://www.ncbi.nlm.nih.gov/pubmed/28855419 [IF:4.423].

Trommelen J, Fuchs CJ, Beelen M, Lenaerts K, Jeukendrup AE, Cermak NM, van Loon LJC. Fructose and Sucrose Intake Increase Exogenous Carbohydrate Oxidation during Exercise. Nutrients. 2017;9(2). https://www.ncbi.nlm.nih.gov/pubmed/28230742 [IF:4.187].

Nyakayiru J, Jonvik KL, Trommelen J, Pinckaers PJ, Senden JM, van Loon LJC, Verdijk LB. Beetroot Juice Supplementation Improves High-Intensity Intermittent Type Exercise Performance in Trained Soccer Players. Nutrients. 2017;9(3). https://www.ncbi.nlm.nih.gov/pubmed/28327503 [IF:4.187].

Gonzalez JT, Fuchs CJ, Betts JA, van Loon LJC. Glucose Plus Fructose Ingestion for Post-Exercise Recovery-Greater than the Sum of Its Parts? Nutrients. 2017;9(4). https://www.ncbi.nlm.nih.gov/pubmed/28358334 [IF:4.187].

Beaudart C, Dawson A, Shaw SC, Harvey NC, Kanis JA, Binkley N, Reginster JY, Chapurlat R, Chan DC, Bruyere O, Rizzoli R, Cooper C, Dennison EM, van Loon LJC as part of the Iof-Esceo Sarcopenia Working Group. Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review. Osteoporos Int. 2017;28(6):1817-33. https://www.ncbi.nlm.nih.gov/pubmed/28251287 [IF:3.906].

Nyakayiru J, Kouw IWK, Cermak NM, Senden JM, van Loon LJC, Verdijk LB. Sodium nitrate ingestion increases skeletal muscle nitrate content in humans. J Appl Physiol (1985). 2017;123(3):637-44. https://www.ncbi.nlm.nih.gov/pubmed/28663382 [IF:3.519].

Dirks ML, Groen BB, Franssen R, van Kranenburg J, van Loon LJC. Neuromuscular electrical stimulation prior to presleep protein feeding stimulates the use of protein-derived amino acids for overnight muscle protein synthesis. J Appl Physiol (1985). 2017;122(1):20-7. https://www.ncbi.nlm.nih.gov/pubmed/27789768 [IF:3.519].

Burke LM, van Loon LJC, Hawley JA. Postexercise muscle glycogen resynthesis in humans. J Appl Physiol (1985). 2017;122(5):1055-67. https://www.ncbi.nlm.nih.gov/pubmed/27789774 [IF:3.519].

Tsintzas K, Stephens FB, Snijders T, Wall BT, Cooper S, Mallinson J, Verdijk LB, van Loon LJC. Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men. Exp Gerontol. 2017;93:36-45. https://www.ncbi.nlm.nih.gov/pubmed/28385599 [IF:3.491].

Nabben M, Schmitz JPJ, Ciapaite J, le Clercq CMP, van Riel NA, Haak HR, Nicolay K, de Coo IFM, Smeets H, Praet SF, van Loon LJC, Prompers JJ. Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in patients with mitochondrial myopathy. Am J Physiol Regul Integr Comp Physiol. 2017;312(5):R689-R701. https://www.ncbi.nlm.nih.gov/pubmed/28179228 [IF:3.290].

Tieland M, Franssen R, Dullemeijer C, van Dronkelaar C, Kyung Kim H, Ispoglou T, Zhu K, Prince RL, van Loon LJC, de Groot L. The Impact of Dietary Protein or Amino Acid Supplementation on Muscle Mass and Strength in Elderly People: Individual Participant Data and Meta-Analysis of RCT’s. J Nutr Health Aging. 2017;21(9):994-1001. https://www.ncbi.nlm.nih.gov/pubmed/29083440 [IF:2.935].

Holwerda AM, Lenaerts K, Bierau J, Wodzig W, van Loon LJC. Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position. Appl Physiol Nutr Metab. 2017;42(7):738-43. https://www.ncbi.nlm.nih.gov/pubmed/28212491 [IF:2.624].

Nyakayiru JM, Jonvik KL, Pinckaers PJ, Senden J, van Loon LJC, Verdijk LB. No Effect of Acute and 6-Day Nitrate Supplementation on VO2 and Time-Trial Performance in Highly Trained Cyclists. Int J Sport Nutr Exerc Metab. 2017;27(1):11-7. https://www.ncbi.nlm.nih.gov/pubmed/27616745 [IF:2.367].

Jonvik KL, Nyakayiru J, van Dijk JW, Wardenaar FC, van Loon LJC, Verdijk LB. Habitual Dietary Nitrate Intake in Highly Trained Athletes. Int J Sport Nutr Exerc Metab. 2017;27(2):148-57. https://www.ncbi.nlm.nih.gov/pubmed/27768510[IF:2.367].

Gillen JB, Trommelen J, Wardenaar FC, Brinkmans NY, Versteegen JJ, Jonvik KL, Kapp C, de Vries J, van den Borne JJ, Gibala MJ, van Loon LJC. Dietary Protein Intake and Distribution Patterns of Well-Trained Dutch Athletes. Int J Sport Nutr Exerc Metab. 2017;27(2):105-14. https://www.ncbi.nlm.nih.gov/pubmed/27710150 [IF:2.367].

Backx E, van der Avoort C, Tieland M, Maase K, Kies A, van Loon LJC, de Groot L, Mensink M. Seasonal Variation in Vitamin D Status in Elite Athletes: A Longitudinal Study. Int J Sport Nutr Exerc Metab. 2017;27(1):6-10. https://www.ncbi.nlm.nih.gov/pubmed/27710147 [IF:2.367].

van der Linden N, Cornelis T, Kimenai DM, Klinkenberg LJJ, Hilderink JM, Luck S, Litjens EJR, Peeters F, Streng AS, Breidthardt T, van Loon LJC, Bekers O, Kooman JP, Westermark PO, Mueller C, Meex SJR. Origin of Cardiac Troponin T Elevations in Chronic Kidney Disease. Circulation. 2017;136(11):1073-5 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/28893963.

van der Linden N, Hilderink JM, Cornelis T, Kimenai DM, Klinkenberg LJJ, van Doorn WP, Litjens EJR, van Suijlen JDE, van Loon LJC, Bekers O, Kooman JP, Meex SJR. Twenty-Four-Hour Biological Variation Profiles of Cardiac Troponin I in Individuals with or without Chronic Kidney Disease. Clin Chem. 2017;63(10):1655-6 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/28814384.

van Dijk JW, van Loon LJC. Commentaries on Viewpoint: A time for exercise: the exercise window. J Appl Physiol (1985). 2017;122(1):210-3 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/28100446.

Snijders T, Nederveen JP, Verdijk LB, Houben A, Goossens GH, Parise G, van Loon LJC. Muscle fiber capillarization as determining factor on indices of insulin sensitivity in humans. Physiol Rep. 2017;5(10):e13278. https://www.ncbi.nlm.nih.gov/pubmed/28550074.

2016

Dirks ML, Wall BT, van de Valk B, Holloway TM, Holloway GP, Chabowski A, Goessens GH, van Loon LJC. One Week of Bed Rest Leads to Substantial Muscle Atrophy and Induces Whole-Body Insulin Resistance in the Absence of Skeletal Muscle Lipid Accumulation. Diabetes. 2016;65(10):2862-75. https://www.ncbi.nlm.nih.gov/pubmed/27358494[IF:8.624].

Klinkenberg LJ, Wildi K, van der Linden N, Kouw IW, Niens M, Twerenbold R, Rubini Gimenez M, Puelacher C, Daniel Neuhaus J, Hillinger P, Nestelberger T, Boeddinghaus J, Grimm K, Sabti Z, Bons JA, van Suijlen JD, Tan FE, Ten Kate J, Bekers O, van Loon LJC, van Dieijen-Visser MP, Mueller C, Meex SJ. Diurnal Rhythm of Cardiac Troponin: Consequences for the Diagnosis of Acute Myocardial Infarction. Clin Chem. 2016;62(12):1602-11. https://www.ncbi.nlm.nih.gov/pubmed/27707754 [IF:7.965].

Hangelbroek RW, Fazelzadeh P, Tieland M, Boekschoten MV, Hooiveld GJ, van Duynhoven JP, Timmons JA, Verdijk LB, de Groot LC, van Loon LJC, Muller M. Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness. J Cachexia Sarcopenia Muscle. 2016;7(5):604-14. https://www.ncbi.nlm.nih.gov/pubmed/27239416 [IF:7.894].

Churchward-Venne TA, Holwerda AM, Phillips SM, van Loon LJC. What is the Optimal Amount of Protein to Support Post-Exercise Skeletal Muscle Reconditioning in the Older Adult? Sports Med. 2016;46(9):1205-12. https://www.ncbi.nlm.nih.gov/pubmed/26894275 [IF:7.622].

Luttikhold J, van Norren K, Rijna H, Buijs N, Ankersmit M, Heijboer AC, Gootjes J, Hartmann B, Holst JJ, van Loon LJC, van Leeuwen PA. Jejunal feeding is followed by a greater rise in plasma cholecystokinin, peptide YY, glucagon-like peptide 1, and glucagon-like peptide 2 concentrations compared with gastric feeding in vivo in humans: a randomized trial. Am J Clin Nutr. 2016;103(2):435-43. https://www.ncbi.nlm.nih.gov/pubmed/26762368 [IF:7.506].

Russell WR, Baka A, Bjorck I, Delzenne N, Gao D, Griffiths HR, Hadjilucas E, Juvonen K, Lahtinen S, Lansink M, van Loon LJC, Mykkanen H, Ostman E, Riccardi G, Vinoy S, Weickert MO. Impact of Diet Composition on Blood Glucose Regulation. Crit Rev Food Sci Nutr. 2016;56(4):541-90. https://www.ncbi.nlm.nih.gov/pubmed/24219323 [IF:6.705].

Groen BB, Horstman AM, Hamer HM, de Haan M, van Kranenburg J, Bierau J, Poeze M, Wodzig WK, Rasmussen BB, van Loon LJC. Increasing Insulin Availability Does Not Augment Postprandial Muscle Protein Synthesis Rates in Healthy Young and Older Men. J Clin Endocrinol Metab. 2016;101(11):3978-88. https://www.ncbi.nlm.nih.gov/pubmed/27745529 [IF:6.215].

Backx EM, Tieland M, Borgonjen-van den Berg KJ, Claessen PR, van Loon LJC, de Groot LC. Protein intake and lean body mass preservation during energy intake restriction in overweight older adults. Int J Obes (Lond). 2016;40(2):299-304. https://www.ncbi.nlm.nih.gov/pubmed/26471344 [IF:5.761].

Sipers WM, Verdijk LB, Sipers SJ, Schols JM, van Loon LJC. The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient. J Am Med Dir Assoc. 2016;17(5):466 e1-7. https://www.ncbi.nlm.nih.gov/pubmed/27107163 [IF:5.449].

Verdijk LB, Snijders T, Holloway TM, van Kranenburg J, van Loon LJC. Resistance Training Increases Skeletal Muscle Capillarization in Healthy Older Men. Med Sci Sports Exerc. 2016;48(11):2157-64. https://www.ncbi.nlm.nih.gov/pubmed/27327032 [IF:5.222].

Trommelen J, Holwerda AM, Kouw IW, Langer H, Halson SL, Rollo I, Verdijk LB, van Loon LJC. Resistance Exercise Augments Postprandial Overnight Muscle Protein Synthesis Rates. Med Sci Sports Exerc. 2016;48(12):2517-25. https://www.ncbi.nlm.nih.gov/pubmed/27643743 [IF:5.222].

Trommelen J, Beelen M, Pinckaers PJ, Senden JM, Cermak NM, van Loon LJC. Fructose Coingestion Does Not Accelerate Postexercise Muscle Glycogen Repletion. Med Sci Sports Exerc. 2016;48(5):907-12. https://www.ncbi.nlm.nih.gov/pubmed/26606271 [IF:5.222].

Whitfield J, Ludzki A, Heigenhauser GJ, Senden JM, Verdijk LB, van Loon LJC, Spriet LL, Holloway GP. Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle. J Physiol. 2016;594(2):421-35. https://www.ncbi.nlm.nih.gov/pubmed/26457670 [IF:4.898].

Fazelzadeh P, Hangelbroek RW, Tieland M, de Groot LC, Verdijk LB, van Loon LJC, Smilde AK, Alves RD, Vervoort J, Muller M, van Duynhoven JP, Boekschoten MV. The Muscle Metabolome Differs between Healthy and Frail Older Adults. J Proteome Res. 2016;15(2):499-509. https://www.ncbi.nlm.nih.gov/pubmed/26732810 [IF:4.430].

Jonvik KL, Nyakayiru J, Pinckaers PJ, Senden JM, van Loon LJC, Verdijk LB. Nitrate-Rich Vegetables Increase Plasma Nitrate and Nitrite Concentrations and Lower Blood Pressure in Healthy Adults. J Nutr. 2016;146(5):986-93. https://www.ncbi.nlm.nih.gov/pubmed/27075914 [IF:4.423].

Holwerda AM, Kouw IW, Trommelen J, Halson SL, Wodzig WK, Verdijk LB, van Loon LJC. Physical Activity Performed in the Evening Increases the Overnight Muscle Protein Synthetic Response to Presleep Protein Ingestion in Older Men. J Nutr. 2016;146(7):1307-14. https://www.ncbi.nlm.nih.gov/pubmed/27281811 [IF:4.423].

Gorissen SH, Horstman AM, Franssen R, Crombag JJ, Langer H, Bierau J, Respondek F, van Loon LJC. Ingestion of Wheat Protein Increases In Vivo Muscle Protein Synthesis Rates in Healthy Older Men in a Randomized Trial. J Nutr. 2016;146(9):1651-9. https://www.ncbi.nlm.nih.gov/pubmed/27440260 [IF:4.423].

Wall BT, Dirks ML, Snijders T, van Dijk JW, Fritsch M, Verdijk LB, van Loon LJC. Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion. Am J Physiol Endocrinol Metab. 2016;310(2):E137-47. https://www.ncbi.nlm.nih.gov/pubmed/26578714 [IF:4.248].

Wall BT, Burd NA, Franssen R, Gorissen SH, Snijders T, Senden JM, Gijsen AP, van Loon LJC. Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning. Am J Physiol Endocrinol Metab. 2016;311(6):E964-E73. https://www.ncbi.nlm.nih.gov/pubmed/27780822 [IF:4.248].

Kouw IW, Cermak NM, Burd NA, Churchward-Venne TA, Senden JM, Gijsen AP, van Loon LJC. Sodium nitrate co-ingestion with protein does not augment postprandial muscle protein synthesis rates in older, type 2 diabetes patients.Am J Physiol Endocrinol Metab. 2016;311(2):E325-34. https://www.ncbi.nlm.nih.gov/pubmed/27221118 [IF:4.248].

Gonzalez JT, Fuchs CJ, Betts JA, van Loon LJC. Liver glycogen metabolism during and after prolonged endurance-type exercise. Am J Physiol Endocrinol Metab. 2016;311(3):E543-53. https://www.ncbi.nlm.nih.gov/pubmed/27436612[IF:4.248].

Dirks ML, Wall BT, Kramer IF, Zorenc AH, Goessens JP, Gijsen AP, van Loon LJC. A single session of neuromuscular electrical stimulation does not augment postprandial muscle protein accretion. Am J Physiol Endocrinol Metab. 2016;311(1):E278-85. https://www.ncbi.nlm.nih.gov/pubmed/27279248 [IF:4.248].

Trommelen J, van Loon LJC. Pre-Sleep Protein Ingestion to Improve the Skeletal Muscle Adaptive Response to Exercise Training. Nutrients. 2016;8(12). https://www.ncbi.nlm.nih.gov/pubmed/27916799 [IF:4.187].

Horstman AM, Olde Damink SW, Schols AM, van Loon LJC. Is Cancer Cachexia Attributed to Impairments in Basal or Postprandial Muscle Protein Metabolism? Nutrients. 2016;8(8). https://www.ncbi.nlm.nih.gov/pubmed/27537909[IF:4.187].

Holwerda AM, Lenaerts K, Bierau J, van Loon LJC. Body Position Modulates Gastric Emptying and Affects the Post-Prandial Rise in Plasma Amino Acid Concentrations Following Protein Ingestion in Humans. Nutrients. 2016;8(4):221. https://www.ncbi.nlm.nih.gov/pubmed/27089362 [IF:4.187].

Marsch E, Theelen TL, Janssen BJ, Briede JJ, Haenen GR, Senden JM, van Loon LJC, Poeze M, Bierau J, Gijbels MJ, Daemen MJ, Sluimer JC. The effect of prolonged dietary nitrate supplementation on atherosclerosis development.Atherosclerosis. 2016;245:212-21. https://www.ncbi.nlm.nih.gov/pubmed/26724532 [IF:4.086].

Snijders T, Smeets JS, van Kranenburg J, Kies AK, van Loon LJC, Verdijk LB. Changes in myonuclear domain size do not precede muscle hypertrophy during prolonged resistance-type exercise training. Acta Physiol (Oxf). 2016;216(2):231-9. https://www.ncbi.nlm.nih.gov/pubmed/26407634 [IF:3.695].

Dirks ML, Backx EM, Wall BT, Verdijk LB, van Loon LJC. May bed rest cause greater muscle loss than limb immobilization? Acta Physiol (Oxf). 2016;218(1):10-2. https://www.ncbi.nlm.nih.gov/pubmed/27124248 [IF:3.695].

Fuchs CJ, Gonzalez JT, Beelen M, Cermak NM, Smith FE, Thelwall PE, Taylor R, Trenell MI, Stevenson EJ, van Loon LJC. Sucrose ingestion after exhaustive exercise accelerates liver, but not muscle glycogen repletion compared with glucose ingestion in trained athletes. J Appl Physiol (1985). 2016;120(11):1328-34. https://www.ncbi.nlm.nih.gov/pubmed/27013608 [IF:3.519].

Klinkenberg LJ, Luyten P, van der Linden N, Urgel K, Snijders DP, Knackstedt C, Dennert R, Kietselaer BL, Mingels AM, Cardinaels EP, Peeters FE, van Suijlen JD, Ten Kate J, Marsch E, Theelen TL, Sluimer JC, Wouters K, Bekers O, Bekkers SC, van Loon LJC, van Dieijen-Visser MP, Meex SJ. Cardiac Troponin T and I Release After a 30-km Run. Am J Cardiol. 2016;118(2):281-7. https://www.ncbi.nlm.nih.gov/pubmed/27282835 [IF:3.444].

van Dijk JW, Eijsvogels TM, Nyakayiru J, Schreuder TH, Hopman MT, Thijssen DH, van Loon LJC. Glycemic control during consecutive days with prolonged walking exercise in individuals with type 1 diabetes mellitus. Diabetes Res Clin Pract. 2016;117:74-81. https://www.ncbi.nlm.nih.gov/pubmed/27329025 [IF:3.308].

Shad BJ, Wallis G, van Loon LJC, Thompson JL. Exercise prescription for the older population: The interactions between physical activity, sedentary time, and adequate nutrition in maintaining musculoskeletal health. Maturitas. 2016;93:78-82. https://www.ncbi.nlm.nih.gov/pubmed/27338978 [IF:3.279].

Backx EM, Tieland M, Maase K, Kies AK, Mensink M, van Loon LJC, de Groot LC. The impact of 1-year vitamin D supplementation on vitamin D status in athletes: a dose-response study. Eur J Clin Nutr. 2016;70(9):1009-14. https://www.ncbi.nlm.nih.gov/pubmed/27460266 [IF:3.226].

van der Linden N, Klinkenberg LJ, Bekers O, van Loon LJC, Dieijen-Visser MP, Zeegers MP, Meex SJ. Prognostic value of basal high-sensitive cardiac troponin levels on mortality in the general population: A meta-analysis. Medicine (Baltimore). 2016;95(52):e5703. https://www.ncbi.nlm.nih.gov/pubmed/28033267 [IF:2.070].

Rozenberg R, Mankowski RT, van Loon LJC, Langendonk JG, Sijbrands EJ, van den Meiracker AH, Stam HJ, Praet SF. Hyperoxia increases arterial oxygen pressure during exercise in type 2 diabetes patients: a feasibility study. Eur J Med Res. 2016;21:1. https://www.ncbi.nlm.nih.gov/pubmed/26744210 [IF:1.521].

Reginster JY, Cooper C, Rizzoli R, Kanis JA, Appelboom G, Bautmans I, Bischoff-Ferrari HA, Boers M, Brandi ML, Bruyere O, Cherubini A, Flamion B, Fielding RA, Gasparik AI, van Loon LJC, McCloskey E, Mitlak BH, Pilotto A, Reiter-Niesert S, Rolland Y, Tsouderos Y, Visser M, Cruz-Jentoft AJ. Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clin Exp Res. 2016;28(1):47-58. https://www.ncbi.nlm.nih.gov/pubmed/26717937[IF:1.393].

Phillips SM, Tipton KD, van Loon LJC, Verdijk LB, Paddon-Jones D, Close GL. Exceptional body composition changes attributed to collagen peptide supplementation and resistance training in older sarcopenic men. Br J Nutr. 2016;116(3):569-70 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/27267663.

2015

Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, Phillips BE, Cederholm T, Jensen T, van Loon LJC, Lannfelt L, Kraus WE, Atherton PJ, Howard R, Gustafsson T, Hodges A, Timmons JA. A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status. Genome Biol. 2015;16:185. https://www.ncbi.nlm.nih.gov/pubmed/26343147 [IF:13.554].

Stephens FB, Chee C, Wall BT, Murton AJ, Shannon CE, van Loon LJC, Tsintzas K. Lipid-induced insulin resistance is associated with an impaired skeletal muscle protein synthetic response to amino acid ingestion in healthy young men.Diabetes. 2015;64(5):1615-20. https://www.ncbi.nlm.nih.gov/pubmed/25524913 [IF:8.624].

Paddon-Jones D, Campbell WW, Jacques PF, Kritchevsky SB, Moore LL, Rodriguez NR, van Loon LJC. Protein and healthy aging. Am J Clin Nutr. 2015. https://www.ncbi.nlm.nih.gov/pubmed/25926511 [IF:7.506].

Liebau F, Wernerman J, van Loon LJC, Rooyackers O. Effect of initiating enteral protein feeding on whole-body protein turnover in critically ill patients. Am J Clin Nutr. 2015;101(3):549-57. https://www.ncbi.nlm.nih.gov/pubmed/25733640[IF:7.506].

Burd NA, Gorissen SH, van Vliet S, Snijders T, van Loon LJC. Differences in postprandial protein handling after beef compared with milk ingestion during postexercise recovery: a randomized controlled trial. Am J Clin Nutr. 2015;102(4):828-36. https://www.ncbi.nlm.nih.gov/pubmed/26354539 [IF:7.506].

Kramer IF, Verdijk LB, Hamer HM, Verlaan S, Luiking Y, Kouw IW, Senden JM, van Kranenburg J, Gijsen AP, Poeze M, van Loon LJC. Impact of the Macronutrient Composition of a Nutritional Supplement on Muscle Protein Synthesis Rates in Older Men: A Randomized, Double Blind, Controlled Trial. J Clin Endocrinol Metab. 2015;100(11):4124-32. https://www.ncbi.nlm.nih.gov/pubmed/26308291 [IF:6.215].

Kouw IW, Gorissen SH, Burd NA, Cermak NM, Gijsen AP, van Kranenburg J, van Loon LJC. Postprandial Protein Handling Is Not Impaired in Type 2 Diabetes Patients When Compared With Normoglycemic Controls. J Clin Endocrinol Metab. 2015;100(8):3103-11. https://www.ncbi.nlm.nih.gov/pubmed/26037513 [IF:6.215].

Liebau F, Sundstrom M, van Loon LJC, Wernerman J, Rooyackers O. Short-term amino acid infusion improves protein balance in critically ill patients. Crit Care. 2015;19:106. https://www.ncbi.nlm.nih.gov/pubmed/25882298 [IF:5.926].

Churchward-Venne TA, Tieland M, Verdijk LB, Leenders M, Dirks ML, de Groot LC, van Loon LJC. There Are No Nonresponders to Resistance-Type Exercise Training in Older Men and Women. J Am Med Dir Assoc. 2015;16(5):400-11. https://www.ncbi.nlm.nih.gov/pubmed/25717010 [IF:5.449].

Dirks ML, Hansen D, Van Assche A, Dendale P, van Loon LJC. Neuromuscular electrical stimulation prevents muscle wasting in critically ill comatose patients. Clin Sci (Lond). 2015;128(6):357-65. https://www.ncbi.nlm.nih.gov/pubmed/25296344 [IF:5.315].

van der Linden N, Klinkenberg LJ, Leenders M, Tieland M, Verdijk LB, Niens M, van Suijlen JD, de Groot LC, Bekers O,van Loon LJC, van Dieijen-Visser MP, Meex SJ. The effect of exercise training on the course of cardiac troponin T and I levels: three independent training studies. Sci Rep. 2015;5:18320. https://www.ncbi.nlm.nih.gov/pubmed/26671282[IF:4.847].

van Vliet S, Burd NA, van Loon LJC. The Skeletal Muscle Anabolic Response to Plant- versus Animal-Based Protein Consumption. J Nutr. 2015;145(9):1981-91. https://www.ncbi.nlm.nih.gov/pubmed/26224750 [IF:4.423].

Snijders T, Res PT, Smeets JS, van Vliet S, van Kranenburg J, Maase K, Kies AK, Verdijk LB, van Loon LJC. Protein Ingestion before Sleep Increases Muscle Mass and Strength Gains during Prolonged Resistance-Type Exercise Training in Healthy Young Men. J Nutr. 2015;145(6):1178-84. https://www.ncbi.nlm.nih.gov/pubmed/25926415 [IF:4.423].

Luttikhold J, van Norren K, Buijs N, Ankersmit M, Heijboer AC, Gootjes J, Rijna H, van Leeuwen PA, van Loon LJC. Jejunal Casein Feeding Is Followed by More Rapid Protein Digestion and Amino Acid Absorption When Compared with Gastric Feeding in Healthy Young Men. J Nutr. 2015;145(9):2033-8. https://www.ncbi.nlm.nih.gov/pubmed/26224751[IF:4.423].

Churchward-Venne TA, Snijders T, Linkens AM, Hamer HM, van Kranenburg J, van Loon LJC. Ingestion of Casein in a Milk Matrix Modulates Dietary Protein Digestion and Absorption Kinetics but Does Not Modulate Postprandial Muscle Protein Synthesis in Older Men. J Nutr. 2015;145(7):1438-45 .https://www.ncbi.nlm.nih.gov/pubmed/26019248[IF:4.423].

Janssens S, Jonkers RA, Groen AK, Nicolay K, van Loon LJC, Prompers JJ. Effects of acute exercise on lipid content and dietary lipid uptake in liver and skeletal muscle of lean and diabetic rats. Am J Physiol Endocrinol Metab. 2015;309(10):E874-83. https://www.ncbi.nlm.nih.gov/pubmed/26419590 [IF:4.248].

Gonzalez JT, Fuchs CJ, Smith FE, Thelwall PE, Taylor R, Stevenson EJ, Trenell MI, Cermak NM, van Loon LJC. Ingestion of glucose or sucrose prevents liver but not muscle glycogen depletion during prolonged endurance-type exercise in trained cyclists. Am J Physiol Endocrinol Metab. 2015;309(12):E1032-9. https://www.ncbi.nlm.nih.gov/pubmed/26487008 [IF:4.248].

Tieland M, Borgonjen-Van den Berg KJ, van Loon LJC, de Groot LC. Dietary Protein Intake in Dutch Elderly People: A Focus on Protein Sources. Nutrients. 2015;7(12):9697-706. https://www.ncbi.nlm.nih.gov/pubmed/26610565[IF:4.187].

Snijders T, Nederveen JP, McKay BR, Joanisse S, Verdijk LB, van Loon LJC, Parise G. Satellite cells in human skeletal muscle plasticity. Front Physiol. 2015;6:283. https://www.ncbi.nlm.nih.gov/pubmed/26557092 [IF:4.187].

Trommelen J, Groen BBL, Hamer HM, De Groot LCPGM, Van Loon LJC. Exogenous insulin does not increase muscle protein synthesis rate when administered systemically: A systematic review. Eur J Endocrinol. 2015;173(1):R25-R34. https://www.scopus.com/inward/record.uri?eid=2-s2.0-84935123161&doi=10.1530%2fEJE-14-0902&partnerID=40&md5=279a280f3553514358f9c26d7ff73161 [IF:4.142].

Trommelen J, Groen BB, Hamer HM, de Groot LC, van Loon LJC. MECHANISMS IN ENDOCRINOLOGY: Exogenous insulin does not increase muscle protein synthesis rate when administered systemically: a systematic review. Eur J Endocrinol. 2015;173(1):R25-34. https://www.ncbi.nlm.nih.gov/pubmed/25646407 [IF:4.142].

Jonvik KL, Nyakayiru J, van Loon LJC, Verdijk LB. Can elite athletes benefit from dietary nitrate supplementation? J Appl Physiol (1985). 2015;119(6):759-61. https://www.ncbi.nlm.nih.gov/pubmed/25997946 [IF:3.519].

Wall BT, Dirks ML, Snijders T, Stephens FB, Senden JM, Verscheijden ML, van Loon LJC. Short-term muscle disuse atrophy is not associated with increased intramuscular lipid deposition or a decline in the maximal activity of key mitochondrial enzymes in young and older males. Exp Gerontol. 2015;61:76-83. https://www.ncbi.nlm.nih.gov/pubmed/25457674 [IF:3.491].

Wall BT, Gorissen SH, Pennings B, Koopman R, Groen BB, Verdijk LB, van Loon LJC. Aging Is Accompanied by a Blunted Muscle Protein Synthetic Response to Protein Ingestion. PLoS One. 2015;10(11):e0140903. https://www.ncbi.nlm.nih.gov/pubmed/26536130 [IF:3.394].

Ninivaggi M, de Laat M, Lance MM, Kicken CH, Pelkmans L, Bloemen S, Dirks ML, van Loon LJC, Govers-Riemslag JW, Lindhout T, Konings J, de Laat B. Hypoxia Induces a Prothrombotic State Independently of the Physical Activity. PLoS One. 2015;10(10):e0141797. https://www.ncbi.nlm.nih.gov/pubmed/26516774 [IF:3.394].

Hursel R, Martens EA, Gonnissen HK, Hamer HM, Senden JM, van Loon LJC, Westerterp-Plantenga MS. Prolonged Adaptation to a Low or High Protein Diet Does Not Modulate Basal Muscle Protein Synthesis Rates – A Substudy. PLoS One. 2015;10(9):e0137183. https://www.ncbi.nlm.nih.gov/pubmed/26367529 [IF:3.394].

Groen BB, Horstman AM, Hamer HM, de Haan M, van Kranenburg J, Bierau J, Poeze M, Wodzig WK, Rasmussen BB, van Loon LJC. Post-Prandial Protein Handling: You Are What You Just Ate. PLoS One. 2015;10(11):e0141582. https://www.ncbi.nlm.nih.gov/pubmed/26556791 [IF:3.394].

Gorissen SH, Remond D, van Loon LJC. The muscle protein synthetic response to food ingestion. Meat Sci. 2015;109:96-100. https://www.ncbi.nlm.nih.gov/pubmed/26021783 [IF:3.313].

Cermak NM, Hansen D, Kouw IW, van Dijk JW, Blackwell JR, Jones AM, Gibala MJ, van Loon LJC. A single dose of sodium nitrate does not improve oral glucose tolerance in patients with type 2 diabetes mellitus. Nutr Res. 2015;35(8):674-80. https://www.ncbi.nlm.nih.gov/pubmed/26092495 [IF:3.183].

Burd NA, Tardif N, Rooyackers O, van Loon LJC. Optimizing the measurement of mitochondrial protein synthesis in human skeletal muscle. Appl Physiol Nutr Metab. 2015;40(1):1-9. https://www.ncbi.nlm.nih.gov/pubmed/25494678[IF:2.624].

Trommelen J, Beelen M, Mullers M, Gibala MJ, van Loon LJC, Cermak NM. A Sucrose Mouth Rinse Does Not Improve 1-hr Cycle Time Trial Performance When Performed in the Fasted or Fed State. Int J Sport Nutr Exerc Metab. 2015;25(6):576-83. https://www.ncbi.nlm.nih.gov/pubmed/26132895 [IF:2.367].

Tieland M, Verdijk LB, de Groot LC, van Loon LJC. Handgrip strength does not represent an appropriate measure to evaluate changes in muscle strength during an exercise intervention program in frail older people. Int J Sport Nutr Exerc Metab. 2015;25(1):27-36. https://www.ncbi.nlm.nih.gov/pubmed/24903908 [IF:2.367].

Wall BT, Morton JP, van Loon LJC. Strategies to maintain skeletal muscle mass in the injured athlete: nutritional considerations and exercise mimetics. Eur J Sport Sci. 2015;15(1):53-62. https://www.ncbi.nlm.nih.gov/pubmed/25027662 [IF:2.323].

Beelen M, Cermak NM, van Loon LJC. [Performance enhancement by carbohydrate intake during sport: effects of carbohydrates during and after high-intensity exercise] – Koolhydraatinname tijdens en na intensieve inspanning. Ned Tijdschr Geneeskd. 2015;159:A7465. https://www.ncbi.nlm.nih.gov/pubmed/25970669.

Jonvik KL, Nyakayiru J, van Loon LJC, Verdijk LB. Last Word on Viewpoint: Can elite athletes benefit from dietary nitrate supplementation? J Appl Physiol (1985). 2015;119(6):770 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/26374878.

Burd NA, Beals JW, van Vliet S, van Loon LJC. Commentaries on Viewpoint: What is the relationship between acute measure of muscle protein synthesis and changes in muscle mass? J Appl Physiol (1985). 2015;118(4):498-503 (Letter to the Editor). https://www.physiology.org/doi/full/10.1152/japplphysiol.01069.2014.

van Dijk JW, van Loon LJC. Exercise strategies to optimize glycemic control in type 2 diabetes: a continuing glucose monitoring perspective. Diabetes Spectr. 2015;28(1):24-31. https://www.ncbi.nlm.nih.gov/pubmed/25717275.

2014

Klinkenberg LJ, van Dijk JW, Tan FE, van Loon LJC, van Dieijen-Visser MP, Meex SJ. Circulating cardiac troponin T exhibits a diurnal rhythm. J Am Coll Cardiol. 2014;63(17):1788-95. https://www.ncbi.nlm.nih.gov/pubmed/24583293[IF:15.776].

Wall BT, Cermak NM, van Loon LJC. Dietary protein considerations to support active aging. Sports Med. 2014;44 Suppl 2:S185-94. https://www.ncbi.nlm.nih.gov/pubmed/25355192 [IF:7.622].

van Loon LJC. Is there a need for protein ingestion during exercise? Sports Med. 2014;44 Suppl 1:S105-11. https://www.ncbi.nlm.nih.gov/pubmed/24791922 [IF:7.622].

Gorissen SH, Burd NA, Hamer HM, Gijsen AP, Groen BB, van Loon LJC. Carbohydrate coingestion delays dietary protein digestion and absorption but does not modulate postprandial muscle protein accretion. J Clin Endocrinol Metab. 2014;99(6):2250-8. https://www.ncbi.nlm.nih.gov/pubmed/24628553 [IF:6.215].

Snijders T, Wall BT, Dirks ML, Senden JM, Hartgens F, Dolmans J, Losen M, Verdijk LB, van Loon LJC. Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content. Clin Sci (Lond). 2014;126(8):557-66. https://www.ncbi.nlm.nih.gov/pubmed/24215591 [IF:5.315].

van Wijck K, Wijnands KA, Meesters DM, Boonen B, van Loon LJC, Buurman WA, Dejong CH, Lenaerts K, Poeze M. L-citrulline improves splanchnic perfusion and reduces gut injury during exercise. Med Sci Sports Exerc. 2014;46(11):2039-46. https://www.ncbi.nlm.nih.gov/pubmed/24621960 [IF:5.222].

Snijders T, Verdijk LB, McKay BR, Smeets JS, van Kranenburg J, Groen BB, Parise G, Greenhaff P, van Loon LJC. Acute dietary protein intake restriction is associated with changes in myostatin expression after a single bout of resistance exercise in healthy young men. J Nutr. 2014;144(2):137-45. https://www.ncbi.nlm.nih.gov/pubmed/24306214[IF:4.423].

Dirks ML, Wall BT, Nilwik R, Weerts DH, Verdijk LB, van Loon LJC. Skeletal muscle disuse atrophy is not attenuated by dietary protein supplementation in healthy older men. J Nutr. 2014;144(8):1196-203. https://www.ncbi.nlm.nih.gov/pubmed/24919692 [IF:4.423].

van der Zwaluw NL, van de Rest O, Tieland M, Adam JJ, Hiddink GJ, van Loon LJC, de Groot LC. The impact of protein supplementation on cognitive performance in frail elderly. Eur J Nutr. 2014;53(3):803-12. https://www.ncbi.nlm.nih.gov/pubmed/24045855 [IF:3.937].

Wall BT, Dirks ML, Snijders T, Senden JM, Dolmans J, van Loon LJC. Substantial skeletal muscle loss occurs during only 5 days of disuse. Acta Physiol (Oxf). 2014;210(3):600-11. https://www.ncbi.nlm.nih.gov/pubmed/24168489 [IF:3.695].

Dirks ML, Wall BT, Snijders T, Ottenbros CL, Verdijk LB, van Loon LJC. Neuromuscular electrical stimulation prevents muscle disuse atrophy during leg immobilization in humans. Acta Physiol (Oxf). 2014;210(3):628-41. https://www.ncbi.nlm.nih.gov/pubmed/24251881 [IF:3.695].

Groen BB, Hamer HM, Snijders T, van Kranenburg J, Frijns D, Vink H, van Loon LJC. Skeletal muscle capillary density and microvascular function are compromised with aging and type 2 diabetes. J Appl Physiol (1985). 2014;116(8):998-1005. https://www.ncbi.nlm.nih.gov/pubmed/24577061 [IF:3.519].

Burd NA, Cermak NM, Kouw IW, Gorissen SH, Gijsen AP, van Loon LJC. The use of doubly labeled milk protein to measure postprandial muscle protein synthesis rates in vivo in humans. J Appl Physiol (1985). 2014;117(11):1363-70. https://www.ncbi.nlm.nih.gov/pubmed/25277738 [IF:3.519].

van de Rest O, van der Zwaluw NL, Tieland M, Adam JJ, Hiddink GJ, van Loon LJC, de Groot LC. Effect of resistance-type exercise training with or without protein supplementation on cognitive functioning in frail and pre-frail elderly: secondary analysis of a randomized, double-blind, placebo-controlled trial. Mech Ageing Dev. 2014;136-137:85-93. https://www.ncbi.nlm.nih.gov/pubmed/24374288 [IF:3.304].

Rizzoli R, Stevenson JC, Bauer JM, van Loon LJC, Walrand S, Kanis JA, Cooper C, Brandi ML, Diez-Perez A, Reginster JY, Force ET. The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: a consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas. 2014;79(1):122-32. https://www.ncbi.nlm.nih.gov/pubmed/25082206 [IF:3.279].

Verdijk LB, Snijders T, Drost M, Delhaas T, Kadi F, van Loon LJC. Satellite cells in human skeletal muscle; from birth to old age. Age (Dordr). 2014;36(2):545-7. https://www.ncbi.nlm.nih.gov/pubmed/24122288 [IF:2.850].

Snijders T, Verdijk LB, Smeets JS, McKay BR, Senden JM, Hartgens F, Parise G, Greenhaff P, van Loon LJC. The skeletal muscle satellite cell response to a single bout of resistance-type exercise is delayed with aging in men. Age (Dordr). 2014;36(4):9699. https://www.ncbi.nlm.nih.gov/pubmed/25108351 [IF:2.850].

Manders RJ, Hansen D, Zorenc AH, Dendale P, Kloek J, Saris WH, van Loon LJC. Protein co-ingestion strongly increases postprandial insulin secretion in type 2 diabetes patients. J Med Food. 2014;17(7):758-63. https://www.ncbi.nlm.nih.gov/pubmed/24611935 [IF:2.060].

van der Linden N, Tieland M, Klinkenberg LJ, Verdijk LB, de Groot LC, van Loon LJC, van Dieijen-Visser MP, Meex SJ. The effect of a six-month resistance-type exercise training program on the course of high sensitive cardiac troponin T levels in (pre)frail elderly. Int J Cardiol. 2014;175(2):374-5 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/24874909.

Rizzoli R, Stevenson JC, Bauer JM, Van Loon LJC, Walrand S, Kanis JA, Cooper C, Brandi ML, Diez-Perez A, Reginster JY. Erratum: The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) (Maturitas (2014) 79 (122-132)). Maturitas. 2015;80(3):337 (Erratum). https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922987100&doi=10.1016%2fj.maturitas.2014.11.005&partnerID=40&md5=79cdc84f1447ff95dba5f6e8af9883a9.

2013

van Dijk JW, Venema M, van Mechelen W, Stehouwer CD, Hartgens F, van Loon LJC. Effect of moderate-intensity exercise versus activities of daily living on 24-hour blood glucose homeostasis in male patients with type 2 diabetes.Diabetes Care. 2013;36(11):3448-53. https://www.ncbi.nlm.nih.gov/pubmed/24041682 [IF:10.037].

Wall BT, Dirks ML, van Loon LJC. Skeletal muscle atrophy during short-term disuse: implications for age-related sarcopenia. Ageing Res Rev. 2013;12(4):898-906. https://www.ncbi.nlm.nih.gov/pubmed/23948422 [IF:8.084].

Cermak NM, van Loon LJC. The use of carbohydrates during exercise as an ergogenic aid. Sports Med. 2013;43(11):1139-55. https://www.ncbi.nlm.nih.gov/pubmed/23846824 [IF:7.622].

Pennings B, Groen BB, van Dijk JW, de Lange A, Kiskini A, Kuklinski M, Senden JM, van Loon LJC. Minced beef is more rapidly digested and absorbed than beef steak, resulting in greater postprandial protein retention in older men. Am J Clin Nutr. 2013;98(1):121-8. https://www.ncbi.nlm.nih.gov/pubmed/23636241 [IF:7.506].

Wall BT, van Loon LJC. Nutritional strategies to attenuate muscle disuse atrophy. Nutr Rev. 2013;71(4):195-208. https://www.ncbi.nlm.nih.gov/pubmed/23550781 [IF:6.428].

Jonkers RA, van Loon LJC, Nicolay K, Prompers JJ. In vivo postprandial lipid partitioning in liver and skeletal muscle in prediabetic and diabetic rats. Diabetologia. 2013;56(3):618-26. https://www.ncbi.nlm.nih.gov/pubmed/23238787[IF:6.358].

Jocken JW, Goossens GH, Boon H, Mason RR, Essers Y, Havekes B, Watt MJ, van Loon LJC, Blaak EE. Insulin-mediated suppression of lipolysis in adipose tissue and skeletal muscle of obese type 2 diabetic men and men with normal glucose tolerance. Diabetologia. 2013;56(10):2255-65. https://www.ncbi.nlm.nih.gov/pubmed/23907381 [IF:6.358].

Wall BT, Snijders T, Senden JM, Ottenbros CL, Gijsen AP, Verdijk LB, van Loon LJC. Disuse impairs the muscle protein synthetic response to protein ingestion in healthy men. J Clin Endocrinol Metab. 2013;98(12):4872-81. https://www.ncbi.nlm.nih.gov/pubmed/24108315 [IF:6.215].

Leenders M, Verdijk LB, van der Hoeven L, van Kranenburg J, Nilwik R, van Loon LJC. Elderly men and women benefit equally from prolonged resistance-type exercise training. J Gerontol A Biol Sci Med Sci. 2013;68(7):769-79. https://www.ncbi.nlm.nih.gov/pubmed/23223011 [IF:5.783].

Mijnarends DM, Meijers JM, Halfens RJ, ter Borg S, Luiking YC, Verlaan S, Schoberer D, Cruz Jentoft AJ, van Loon LJC, Schols JM. Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people: a systematic review. J Am Med Dir Assoc. 2013;14(3):170-8. https://www.ncbi.nlm.nih.gov/pubmed/23276432 [IF:5.449].

Leenders M, Verdijk LB, van der Hoeven L, Adam JJ, van Kranenburg J, Nilwik R, van Loon LJC. Patients with type 2 diabetes show a greater decline in muscle mass, muscle strength, and functional capacity with aging. J Am Med Dir Assoc. 2013;14(8):585-92. https://www.ncbi.nlm.nih.gov/pubmed/23537893 [IF:5.449].

Brouwer-Brolsma EM, van de Rest O, Tieland M, van der Zwaluw NL, Steegenga WT, Adam JJ, van Loon LJC, Feskens EJ, de Groot LC. Serum 25-hydroxyvitamin D is associated with cognitive executive function in Dutch prefrail and frail elderly: a cross-sectional study exploring the associations of 25-hydroxyvitamin D with glucose metabolism, cognitive performance and depression. J Am Med Dir Assoc. 2013;14(11):852 e9-17. https://www.ncbi.nlm.nih.gov/pubmed/23921196 [IF:5.449].

Burd NA, Gorissen SH, van Loon LJC. Anabolic resistance of muscle protein synthesis with aging. Exerc Sport Sci Rev. 2013;41(3):169-73. https://www.ncbi.nlm.nih.gov/pubmed/23558692 [IF:5.429].

Van Dijk JW, Manders RJ, Canfora EE, Mechelen WV, Hartgens F, Stehouwer CD, van Loon LJC. Exercise and 24-h glycemic control: equal effects for all type 2 diabetes patients? Med Sci Sports Exerc. 2013;45(4):628-35. https://www.ncbi.nlm.nih.gov/pubmed/23507836 [IF:5.222].

Res PT, Cermak NM, Stinkens R, Tollakson TJ, Haenen GR, Bast A, van Loon LJC. Astaxanthin supplementation does not augment fat use or improve endurance performance. Med Sci Sports Exerc. 2013;45(6):1158-65. https://www.ncbi.nlm.nih.gov/pubmed/23274592 [IF:5.222].

Leenders M, Verdijk LB, Van der Hoeven L, Van Kranenburg J, Nilwik R, Wodzig WK, Senden JM, Keizer HA, van Loon LJC. Protein supplementation during resistance-type exercise training in the elderly. Med Sci Sports Exerc. 2013;45(3):542-52.https://www.ncbi.nlm.nih.gov/pubmed/22968306 [IF:5.222].

Cermak NM, Snijders T, McKay BR, Parise G, Verdijk LB, Tarnopolsky MA, Gibala MJ, van Loon LJC. Eccentric exercise increases satellite cell content in type II muscle fibers. Med Sci Sports Exerc. 2013;45(2):230-7. https://www.ncbi.nlm.nih.gov/pubmed/22968308 [IF:5.222].

Wall BT, Hamer HM, de Lange A, Kiskini A, Groen BB, Senden JM, Gijsen AP, Verdijk LB, van Loon LJC. Leucine co-ingestion improves post-prandial muscle protein accretion in elderly men. Clin Nutr. 2013;32(3):412-9. https://www.ncbi.nlm.nih.gov/pubmed/23043721 [IF:4.916].

Nabuurs CI, Choe CU, Veltien A, Kan HE, van Loon LJC, Rodenburg RJ, Matschke J, Wieringa B, Kemp GJ, Isbrandt D, Heerschap A. Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake. J Physiol. 2013;591(2):571-92. https://www.ncbi.nlm.nih.gov/pubmed/23129796 [IF:4.898].

Huidekoper HH, Ackermans MT, Koopman R, van Loon LJC, Sauerwein HP, Wijburg FA. Normal rates of whole-body fat oxidation and gluconeogenesis after overnight fasting and moderate-intensity exercise in patients with medium-chain acyl-CoA dehydrogenase deficiency. J Inherit Metab Dis. 2013;36(5):831-40. https://www.ncbi.nlm.nih.gov/pubmed/22976767 [IF:3.710].

Hamer HM, Wall BT, Kiskini A, de Lange A, Groen BB, Bakker JA, Gijsen AP, Verdijk LB, van Loon LJC. Carbohydrate co-ingestion with protein does not further augment post-prandial muscle protein accretion in older men. Nutr Metab (Lond). 2013;10(1):15. https://www.ncbi.nlm.nih.gov/pubmed/23351781 [IF:3.525].

Nilwik R, Snijders T, Leenders M, Groen BB, van Kranenburg J, Verdijk LB, van Loon LJC. The decline in skeletal muscle mass with aging is mainly attributed to a reduction in type II muscle fiber size. Exp Gerontol. 2013;48(5):492-8. https://www.ncbi.nlm.nih.gov/pubmed/23425621 [IF:3.491].

Klinkenberg LJ, Res PT, Haenen GR, Bast A, van Loon LJC, van Dieijen-Visser MP, Meex SJ. Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: a randomized trial. PLoS One. 2013;8(11):e79280. https://www.ncbi.nlm.nih.gov/pubmed/24260184 [IF:3.394].

Burd NA, Hamer HM, Pennings B, Pellikaan WF, Senden JM, Gijsen AP, van Loon LJC. Substantial Differences between Organ and Muscle Specific Tracer Incorporation Rates in a Lactating Dairy Cow. PLoS One. 2013;8(6):e68109. https://www.ncbi.nlm.nih.gov/pubmed/23826365 [IF:3.394].

van Wijck K, Pennings B, van Bijnen AA, Senden JM, Buurman WA, Dejong CH, van Loon LJC, Lenaerts K. Dietary protein digestion and absorption are impaired during acute postexercise recovery in young men. Am J Physiol Regul Integr Comp Physiol. 2013;304(5):R356-61. https://www.ncbi.nlm.nih.gov/pubmed/23283940 [IF:3.290].

Tieland M, Brouwer-Brolsma EM, Nienaber-Rousseau C, van Loon LJC, De Groot LC. Low vitamin D status is associated with reduced muscle mass and impaired physical performance in frail elderly people. Eur J Clin Nutr. 2013;67(10):1050-5. https://www.ncbi.nlm.nih.gov/pubmed/23942175 [IF:3.226].

Cooper C, Fielding R, Visser M, van Loon LJC, Rolland Y, Orwoll E, Reid K, Boonen S, Dere W, Epstein S, Mitlak B, Tsouderos Y, Sayer AA, Rizzoli R, Reginster JY, Kanis JA. Tools in the assessment of sarcopenia. Calcif Tissue Int. 2013;93(3):201-10. https://www.ncbi.nlm.nih.gov/pubmed/23842964 [IF:3.091].

Kiskini A, Hamer HM, Wall BT, Groen BB, de Lange A, Bakker JA, Senden JM, Verdijk LB, van Loon LJC. The muscle protein synthetic response to the combined ingestion of protein and carbohydrate is not impaired in healthy older men. Age (Dordr). 2013;35(6):2389-98. https://www.ncbi.nlm.nih.gov/pubmed/23529503 [IF:2.850].

Zbinden-Foncea H, van Loon LJC, Raymackers JM, Francaux M, Deldicque L. Contribution of nonesterified fatty acids to mitogen-activated protein kinase activation in human skeletal muscle during endurance exercise. Int J Sport Nutr Exerc Metab. 2013;23(3):201-9. https://www.ncbi.nlm.nih.gov/pubmed/23114833 [IF:2.367].

Wall BT, Stephens FB, van Loon LJC, Constantin-Teodosiu D, Macdonald IA, Greenhaff PL. Reduced fat oxidation during high intensity, submaximal exercise: Is the availability of carnitine important? Eur J Sport Sci. 2013;13(2):191-9. https://www.scopus.com/inward/record.uri?eid=2-s2.0-84875298781&doi=10.1080%2f17461391.2011.630103&partnerID=40&md5=8c46c9c9d9f9d294b5578377fc4db8c0[IF:2.323].

van Dijk JW, Manders RJF, Tummers K, Bonomi AG, Stehouwer CDA, Hartgens F, van Loon LJC. Kracht- en duurinspanning verbeteren 24-uurs bloedglucosehomeostase bij personen met een verminderde glucosetolerantie bij patiënten met type 2 diabetes. Ned Tijdschr Diabet. 2013;11(2):52-3. https://link.springer.com/article/10.1007/s12467-013-0019-5.

Tieland M, de Groot L, van Loon LJC. [Recent research: egg white supplementation during longterm resistance training increases muscle mass in the frail elderly] – Recent onderzoek : Eiwitsuppletie tijdens langdurige krachttraining vergroot de spiermassatoename in fragiele ouderen. Tijdschr Gerontol Geriatr. 2013;44(2):90-1. https://www.ncbi.nlm.nih.gov/pubmed/23494687.

van Dijk JW, van Loon LJC. Response to comment on: van Dijk et al. Exercise therapy in type 2 diabetes: is daily exercise required to optimize glycemic control? Diabetes Care 2012;35:948-954. Diabetes Care. 2013;36(5):e74 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/23613614.

Cermak NM, de Groot LC, van Loon LJC. Perspective: Protein supplementation during prolonged resistance type exercise training augments skeletal muscle mass and strength gains. J Am Med Dir Assoc. 2013;14(1):71-2 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/23158847.

van Dijk JW, Tummers K, Stehouwer CD, Hartgens F, van Loon LJC. Exercise therapy in type 2 diabetes: Is daily exercise required to optimize glycemic control? Diabetes Technology and Therapeutics. 2013;15(SUPPL.1):S97-S8 (Commentary). https://www.scopus.com/inward/record.uri?eid=2-s2.0-84896890224&doi=10.1089%2fdia.2013.1511&partnerID=40&md5=3b4dee22375a4857194ecb43dd02e602.

Van Dijk JW, Manders RJ, Tummers K, Bonomi AG, Stehouwer CD, Hartgens F, van Loon LJC. Both resistance- and endurance-type exercise reduce the prevalence of hyperglycemia in individuals with impaired glucose tolerance and in insulin-treated and non-insulin-treated type 2 diabetic patients. Diabetes Technology and Therapeutics. 2013;15(SUPPL.1):S99-S100 (Commentary). https://www.scopus.com/inward/record.uri?eid=2-s2.0-84896869845&doi=10.1089%2fdia.2013.1511&partnerID=40&md5=46fdca2e386a5b559c8d5d939282bc4b.

van Loon LJC, Tipton KD. Concluding remarks: nutritional strategies to support the adaptive response to prolonged exercise training. Nestle Nutr Inst Workshop Ser. 2013;75:135-41. https://www.ncbi.nlm.nih.gov/pubmed/23765357.

van Loon LJC, Meeusen R. Limits of human endurance. Preface. Nestle Nutr Inst Workshop Ser. 2013;76:VII. https://www.ncbi.nlm.nih.gov/pubmed/23899760.

van Loon LJC, Meeusen R. Concluding remarks: Nutritional strategies to increase performance capacity. Nestle Nutr Inst Workshop Ser. 2013;76:121-5 .https://www.ncbi.nlm.nih.gov/pubmed/23899759.

van Loon LJC. Role of dietary protein in post-exercise muscle reconditioning. Nestle Nutr Inst Workshop Ser. 2013;75:73-83. https://www.ncbi.nlm.nih.gov/pubmed/23765352.

Aguirre N, van Loon LJC, Baar K. The role of amino acids in skeletal muscle adaptation to exercise. Nestle Nutr Inst Workshop Ser. 2013;76:85-102. https://www.ncbi.nlm.nih.gov/pubmed/23899757.

2012

van Dijk JW, Tummers K, Stehouwer CD, Hartgens F, van Loon LJC. Exercise therapy in type 2 diabetes: is daily exercise required to optimize glycemic control? Diabetes Care. 2012;35(5):948-54. https://www.ncbi.nlm.nih.gov/pubmed/22399700 [IF:10.037].

Cermak NM, Res PT, de Groot LC, Saris WH, van Loon LJC. Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis. Am J Clin Nutr. 2012;96(6):1454-64. https://www.ncbi.nlm.nih.gov/pubmed/23134885 [IF:7.506].

van Dijk JW, Manders RJ, Tummers K, Bonomi AG, Stehouwer CD, Hartgens F, van Loon LJC. Both resistance- and endurance-type exercise reduce the prevalence of hyperglycaemia in individuals with impaired glucose tolerance and in insulin-treated and non-insulin-treated type 2 diabetic patients. Diabetologia. 2012;55(5):1273-82. https://www.ncbi.nlm.nih.gov/pubmed/22124605 [IF:6.358].

van Tienen FH, Praet SF, de Feyter HM, van den Broek NM, Lindsey PJ, Schoonderwoerd KG, de Coo IF, Nicolay K, Prompers JJ, Smeets HJ, van Loon LJC. Physical activity is the key determinant of skeletal muscle mitochondrial function in type 2 diabetes. J Clin Endocrinol Metab. 2012;97(9):3261-9. https://www.ncbi.nlm.nih.gov/pubmed/22802091 [IF:6.215].

Tieland M, van de Rest O, Dirks ML, van der Zwaluw N, Mensink M, van Loon LJC, de Groot LC. Protein supplementation improves physical performance in frail elderly people: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc. 2012;13(8):720-6. https://www.ncbi.nlm.nih.gov/pubmed/22889730 [IF:5.449].

Tieland M, Dirks ML, van der Zwaluw N, Verdijk LB, van de Rest O, de Groot LC, van Loon LJC. Protein supplementation increases muscle mass gain during prolonged resistance-type exercise training in frail elderly people: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc. 2012;13(8):713-9. https://www.ncbi.nlm.nih.gov/pubmed/22770932 [IF:5.449].

Verdijk LB, Dirks ML, Snijders T, Prompers JJ, Beelen M, Jonkers RA, Thijssen DH, Hopman MT, van Loon LJC. Reduced satellite cell numbers with spinal cord injury and aging in humans. Med Sci Sports Exerc. 2012;44(12):2322-30.https://www.ncbi.nlm.nih.gov/pubmed/22776875 [IF:5.222].

van Wijck K, Lenaerts K, van Bijnen AA, Boonen B, van Loon LJC, Dejong CH, Buurman WA. Aggravation of exercise-induced intestinal injury by Ibuprofen in athletes. Med Sci Sports Exerc. 2012;44(12):2257-62. https://www.ncbi.nlm.nih.gov/pubmed/22776871 [IF:5.222].

Res PT, Groen B, Pennings B, Beelen M, Wallis GA, Gijsen AP, Senden JM, van Loon LJC. Protein ingestion before sleep improves postexercise overnight recovery. Med Sci Sports Exerc. 2012;44(8):1560-9. https://www.ncbi.nlm.nih.gov/pubmed/22330017 [IF:5.222].

Beelen M, Kranenburg J, Senden JM, Kuipers H, van Loon LJC. Impact of caffeine and protein on postexercise muscle glycogen synthesis. Med Sci Sports Exerc. 2012;44(4):692-700. https://www.ncbi.nlm.nih.gov/pubmed/21986807[IF:5.222].

Haegens A, Schols AM, van Essen AL, van Loon LJC, Langen RC. Leucine induces myofibrillar protein accretion in cultured skeletal muscle through mTOR dependent and -independent control of myosin heavy chain mRNA levels. Mol Nutr Food Res. 2012;56(5):741-52. https://www.ncbi.nlm.nih.gov/pubmed/22648621 [IF:4.518].

Burd NA, Groen BB, Beelen M, Senden JM, Gijsen AP, van Loon LJC. The reliability of using the single-biopsy approach to assess basal muscle protein synthesis rates in vivo in humans. Metabolism. 2012;61(7):931-6. https://www.ncbi.nlm.nih.gov/pubmed/22209666 [IF:4.258].

Wall BT, Dirks ML, Verdijk LB, Snijders T, Hansen D, Vranckx P, Burd NA, Dendale P, van Loon LJC. Neuromuscular electrical stimulation increases muscle protein synthesis in elderly type 2 diabetic men. Am J Physiol Endocrinol Metab. 2012;303(5):E614-23. https://www.ncbi.nlm.nih.gov/pubmed/22739107 [IF:4.248].

Shaw CS, Shepherd SO, Wagenmakers AJ, Hansen D, Dendale P, van Loon LJC. Prolonged exercise training increases intramuscular lipid content and perilipin 2 expression in type I muscle fibers of patients with type 2 diabetes. Am J Physiol Endocrinol Metab. 2012;303(9):E1158-65. https://www.ncbi.nlm.nih.gov/pubmed/22949030 [IF:4.248].

Pennings B, Groen B, de Lange A, Gijsen AP, Zorenc AH, Senden JM, van Loon LJC. Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men. Am J Physiol Endocrinol Metab. 2012;302(8):E992-9. https://www.ncbi.nlm.nih.gov/pubmed/22338070 [IF:4.248].

Jonkers RA, Dirks ML, Nabuurs CI, De Feyter HM, Praet SF, Nicolay K, van Loon LJC, Prompers JJ. Myofibrillar distribution of succinate dehydrogenase activity and lipid stores differs in skeletal muscle tissue of paraplegic subjects.Am J Physiol Endocrinol Metab. 2012;302(3):E365-73. https://www.ncbi.nlm.nih.gov/pubmed/22068603 [IF:4.248].

Groen BB, Res PT, Pennings B, Hertle E, Senden JM, Saris WH, van Loon LJC. Intragastric protein administration stimulates overnight muscle protein synthesis in elderly men. Am J Physiol Endocrinol Metab. 2012;302(1):E52-60. https://www.ncbi.nlm.nih.gov/pubmed/21917635 [IF:4.248].

van Loon LJC. Leucine as a pharmaconutrient in health and disease. Curr Opin Clin Nutr Metab Care. 2012;15(1):71-7. https://www.ncbi.nlm.nih.gov/pubmed/22037013 [IF:4.009].

Jonkers RA, Geraedts TR, van Loon LJC, Nicolay K, Prompers JJ. Multitissue assessment of in vivo postprandial intracellular lipid partitioning in rats using localized 1H-[13C] magnetic resonance spectroscopy. Magn Reson Med. 2012;68(4):997-1006. https://www.ncbi.nlm.nih.gov/pubmed/22213012 [IF:3.993].

Tieland M, Borgonjen-Van den Berg KJ, van Loon LJC, de Groot LC. Dietary protein intake in community-dwelling, frail, and institutionalized elderly people: scope for improvement. Eur J Nutr. 2012;51(2):173-9. https://www.ncbi.nlm.nih.gov/pubmed/21562887 [IF:3.937].

van Wijck K, Lenaerts K, Grootjans J, Wijnands KA, Poeze M, van Loon LJC, Dejong CH, Buurman WA. Physiology and pathophysiology of splanchnic hypoperfusion and intestinal injury during exercise: strategies for evaluation and prevention. Am J Physiol Gastrointest Liver Physiol. 2012;303(2):G155-68. https://www.ncbi.nlm.nih.gov/pubmed/22517770 [IF:3.788].

van Can JG, van Loon LJC, Brouns F, Blaak EE. Reduced glycaemic and insulinaemic responses following trehalose and isomaltulose ingestion: implications for postprandial substrate use in impaired glucose-tolerant subjects. Br J Nutr. 2012;108(7):1210-7. https://www.ncbi.nlm.nih.gov/pubmed/22172468 [IF:3.784].

Burd NA, Wall BT, van Loon LJC. The curious case of anabolic resistance: old wives’ tales or new fables? J Appl Physiol (1985). 2012;112(7):1233-5. https://www.ncbi.nlm.nih.gov/pubmed/22134695 [IF:3.519].

Burd NA, Pennings B, Groen BB, Gijsen AP, Senden JM, van Loon LJC. The single biopsy approach is reliable for the measurement of muscle protein synthesis rates in vivo in older men. J Appl Physiol (1985). 2012;113(6):896-902 .https://www.ncbi.nlm.nih.gov/pubmed/22815390 [IF:3.519].

Li M, Verdijk LB, Sakamoto K, Ely B, van Loon LJC, Musi N. Reduced AMPK-ACC and mTOR signaling in muscle from older men, and effect of resistance exercise. Mech Ageing Dev. 2012;133(11-12):655-64. https://www.ncbi.nlm.nih.gov/pubmed/23000302 [IF:3.304].

Snijders T, Verdijk LB, Beelen M, McKay BR, Parise G, Kadi F, van Loon LJC. A single bout of exercise activates skeletal muscle satellite cells during subsequent overnight recovery. Exp Physiol. 2012;97(6):762-73. https://www.ncbi.nlm.nih.gov/pubmed/22327327 [IF:2.937].

van Dijk JW, Tummers K, Hamer HM, van Loon LJC. Vinegar co-ingestion does not improve oral glucose tolerance in patients with type 2 diabetes. J Diabetes Complications. 2012;26(5):460-1. https://www.ncbi.nlm.nih.gov/pubmed/22699111 [IF:2.814].

Cermak NM, Res P, Stinkens R, Lundberg JO, Gibala MJ, van Loon LJC. No improvement in endurance performance after a single dose of beetroot juice. Int J Sport Nutr Exerc Metab. 2012;22(6):470-8. https://www.ncbi.nlm.nih.gov/pubmed/22805107 [IF:2.367].

Cermak NM, Gibala MJ, van Loon LJC. Nitrate supplementation’s improvement of 10-km time-trial performance in trained cyclists. Int J Sport Nutr Exerc Metab. 2012;22(1):64-71. https://www.ncbi.nlm.nih.gov/pubmed/22248502[IF:2.367].

van Dijk JW, Tummers K, Stehouwer CD, Hartgens F, van Loon LJC. Inspanningstherapie bij type 2 diabetes: is dagelijkse inspanning noodzakelijk om glycemische controle te optimaliseren? . Ned Tijdschr Diabet. 2012;10(2):60-1. https://link.springer.com/article/10.1007%2Fs12467-012-0021-3.

Klinkenberg LJ, Res PT, van Loon LJC, van Dieijen-Visser MP, Meex SJ. Strong link between basal and exercise-induced cardiac troponin T levels: do both reflect risk? Int J Cardiol. 2012;158(1):129-31 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/22560936.

Burd NA, Wall BT, van Loon LJC. Last word on viewpoint: the curious case of anabolic resistance: old wives’ tales or new fables? J Appl Physiol (1985). 2012;112(7):1237 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/22467757.

2011

Pennings B, Koopman R, Beelen M, Senden JM, Saris WH, van Loon LJC. Exercising before protein intake allows for greater use of dietary protein-derived amino acids for de novo muscle protein synthesis in both young and elderly men. Am J Clin Nutr. 2011;93(2):322-31. https://www.ncbi.nlm.nih.gov/pubmed/21084649 [IF:7.506].

Pennings B, Boirie Y, Senden JM, Gijsen AP, Kuipers H, van Loon LJC. Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men. Am J Clin Nutr. 2011;93(5):997-1005. https://www.ncbi.nlm.nih.gov/pubmed/21367943 [IF:7.506].

Leenders M, van Loon LJC. Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes. Nutr Rev. 2011;69(11):675-89. https://www.ncbi.nlm.nih.gov/pubmed/22029833 [IF:6.428].

Leenders M, Verdijk LB, van der Hoeven L, van Kranenburg J, Hartgens F, Wodzig WK, Saris WH, van Loon LJC. Prolonged leucine supplementation does not augment muscle mass or affect glycemic control in elderly type 2 diabetic men. J Nutr. 2011;141(6):1070-6. https://www.ncbi.nlm.nih.gov/pubmed/21525248 [IF:4.423].

Beelen M, Zorenc A, Pennings B, Senden JM, Kuipers H, van Loon LJC. Impact of protein coingestion on muscle protein synthesis during continuous endurance type exercise. Am J Physiol Endocrinol Metab. 2011;300(6):E945-54. https://www.ncbi.nlm.nih.gov/pubmed/21364122 [IF:4.248].

van Wijck K, Lenaerts K, van Loon LJC, Peters WH, Buurman WA, Dejong CH. Exercise-induced splanchnic hypoperfusion results in gut dysfunction in healthy men. PLoS One. 2011;6(7):e22366. https://www.ncbi.nlm.nih.gov/pubmed/21811592 [IF:3.394].

van Dijk JW, Manders RJ, Hartgens F, Stehouwer CD, Praet SF, van Loon LJC. Postprandial hyperglycemia is highly prevalent throughout the day in type 2 diabetes patients. Diabetes Res Clin Pract. 2011;93(1):31-7. https://www.ncbi.nlm.nih.gov/pubmed/21497935 [IF:3.308].

Phillips SM, van Loon LJC. Dietary protein for athletes: from requirements to optimum adaptation. J Sports Sci. 2011;29 Suppl 1:S29-38. https://www.ncbi.nlm.nih.gov/pubmed/22150425 [IF:3.043].

Pennings B, Pellikaan WF, Senden JM, van Vuuren AM, Sikkema J, van Loon LJC. The production of intrinsically labeled milk and meat protein is feasible and provides functional tools for human nutrition research. J Dairy Sci. 2011;94(9):4366-73. https://www.ncbi.nlm.nih.gov/pubmed/21854909 [IF:2.855].

Koopman R, Gleeson BG, Gijsen AP, Groen B, Senden JM, Rennie MJ, van Loon LJC. Post-exercise protein synthesis rates are only marginally higher in type I compared with type II muscle fibres following resistance-type exercise. Eur J Appl Physiol. 2011;111(8):1871-8. https://www.ncbi.nlm.nih.gov/pubmed/21234594 [IF:2.567].

Snijders T, Verdijk LB, Hansen D, Dendale P, van Loon LJC. Continuous endurance-type exercise training does not modulate satellite cell content in obese type 2 diabetes patients. Muscle Nerve. 2011;43(3):393-401. https://www.ncbi.nlm.nih.gov/pubmed/21321955 [IF:2.560].

Bosselaar M, Smits P, van Loon LJC, Tack CJ. Intravenous AICAR during hyperinsulinemia induces systemic hemodynamic changes but has no local metabolic effect. J Clin Pharmacol. 2011;51(10):1449-58. https://www.ncbi.nlm.nih.gov/pubmed/21148051 [IF:2.482].

Betts JA, Beelen M, Stokes KA, Saris WH, van Loon LJC. Endocrine responses during overnight recovery from exercise: impact of nutrition and relationships with muscle protein synthesis. Int J Sport Nutr Exerc Metab. 2011;21(5):398-409. https://www.ncbi.nlm.nih.gov/pubmed/21832304 [IF:2.367].

van Loon LJC, Gibala MJ. Dietary protein to support muscle hypertrophy. Nestle Nutr Inst Workshop Ser. 2011;69:79-89; discussion -95. https://www.ncbi.nlm.nih.gov/pubmed/22301837.

2010

Hansen D, Dendale P, van Loon LJC, Meeusen R. The impact of training modalities on the clinical benefits of exercise intervention in patients with cardiovascular disease risk or type 2 diabetes mellitus. Sports Med. 2010;40(11):921-40. https://www.ncbi.nlm.nih.gov/pubmed/20942509 [IF:7.622].

Jocken JW, Moro C, Goossens GH, Hansen D, Mairal A, Hesselink MK, Langin D, van Loon LJC, Blaak EE. Skeletal muscle lipase content and activity in obesity and type 2 diabetes. J Clin Endocrinol Metab. 2010;95(12):5449-53. https://www.ncbi.nlm.nih.gov/pubmed/20843949 [IF:6.215].

Manders RJ, Van Dijk JW, van Loon LJC. Low-intensity exercise reduces the prevalence of hyperglycemia in type 2 diabetes. Med Sci Sports Exerc. 2010;42(2):219-25. https://www.ncbi.nlm.nih.gov/pubmed/19927038 [IF:5.222].

Verdijk LB, Snijders T, Beelen M, Savelberg HH, Meijer K, Kuipers H, van Loon LJC. Characteristics of muscle fiber type are predictive of skeletal muscle mass and strength in elderly men. J Am Geriatr Soc. 2010;58(11):2069-75. https://www.ncbi.nlm.nih.gov/pubmed/21054286 [IF:5.185].

Timmons JA, Knudsen S, Rankinen T, Koch LG, Sarzynski M, Jensen T, Keller P, Scheele C, Vollaard NB, Nielsen S, Akerstrom T, MacDougald OA, Jansson E, Greenhaff PL, Tarnopolsky MA, van Loon LJC, Pedersen BK, Sundberg CJ, Wahlestedt C, Britton SL, Bouchard C. Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985). 2010;108(6):1487-96. https://www.ncbi.nlm.nih.gov/pubmed/20133430 [IF:3.519].

Wisse W, Boer Rookhuizen M, de Kruif MD, van Rossum J, Jordans I, ten Cate H, van Loon LJC, Meesters EW. Prescription of physical activity is not sufficient to change sedentary behavior and improve glycemic control in type 2 diabetes patients. Diabetes Res Clin Pract. 2010;88(2):e10-3. https://www.ncbi.nlm.nih.gov/pubmed/20138384[IF:3.308].

Hansen D, Dendale P, Beelen M, Jonkers RA, Mullens A, Corluy L, Meeusen R, van Loon LJC. Plasma adipokine and inflammatory marker concentrations are altered in obese, as opposed to non-obese, type 2 diabetes patients. Eur J Appl Physiol. 2010;109(3):397-404. https://www.ncbi.nlm.nih.gov/pubmed/20131064 [IF:2.567].

Beelen M, Burke LM, Gibala MJ, van Loon LJC. Nutritional strategies to promote postexercise recovery. Int J Sport Nutr Exerc Metab. 2010;20(6):515-32. https://www.ncbi.nlm.nih.gov/pubmed/21116024 [IF:2.367].

2009

Snijders T, Verdijk LB, van Loon LJC. The impact of sarcopenia and exercise training on skeletal muscle satellite cells.Ageing Res Rev. 2009;8(4):328-38. https://www.ncbi.nlm.nih.gov/pubmed/19464390 [IF:8.084].

Verhoeven S, Vanschoonbeek K, Verdijk LB, Koopman R, Wodzig WK, Dendale P, van Loon LJC. Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men. Am J Clin Nutr. 2009;89(5):1468-75. https://www.ncbi.nlm.nih.gov/pubmed/19321567 [IF:7.506].

Verdijk LB, Jonkers RA, Gleeson BG, Beelen M, Meijer K, Savelberg HH, Wodzig WK, Dendale P, van Loon LJC. Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men. Am J Clin Nutr. 2009;89(2):608-16. https://www.ncbi.nlm.nih.gov/pubmed/19106243[IF:7.506].

Manders RJ, Pennings B, Beckers CP, Aipassa TI, van Loon LJC. Prevalence of daily hyperglycemia in obese type 2 diabetic men compared with that in lean and obese normoglycemic men: effect of consumption of a sucrose-containing beverage. Am J Clin Nutr. 2009;90(3):511-8. https://www.ncbi.nlm.nih.gov/pubmed/19605567 [IF:7.506].

Koopman R, Crombach N, Gijsen AP, Walrand S, Fauquant J, Kies AK, Lemosquet S, Saris WH, Boirie Y, van Loon LJC. Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein. Am J Clin Nutr. 2009;90(1):106-15. https://www.ncbi.nlm.nih.gov/pubmed/19474134[IF:7.506].

Hansen D, Dendale P, Jonkers RA, Beelen M, Manders RJ, Corluy L, Mullens A, Berger J, Meeusen R, van Loon LJC. Continuous low- to moderate-intensity exercise training is as effective as moderate- to high-intensity exercise training at lowering blood HbA(1c) in obese type 2 diabetes patients. Diabetologia. 2009;52(9):1789-97. https://www.ncbi.nlm.nih.gov/pubmed/19370339 [IF:6.358].

Verdijk LB, Gleeson BG, Jonkers RA, Meijer K, Savelberg HH, Dendale P, van Loon LJC. Skeletal muscle hypertrophy following resistance training is accompanied by a fiber type-specific increase in satellite cell content in elderly men. J Gerontol A Biol Sci Med Sci. 2009;64(3):332-9. https://www.ncbi.nlm.nih.gov/pubmed/19196907 [IF:5.783].

Witard OC, Tieland M, Beelen M, Tipton KD, van Loon LJC, Koopman R. Resistance exercise increases postprandial muscle protein synthesis in humans. Med Sci Sports Exerc. 2009;41(1):144-54. https://www.ncbi.nlm.nih.gov/pubmed/19092695 [IF:5.222].

Weseler AR, Geraets L, Moonen HJ, Manders RJ, van Loon LJC, Pennings HJ, Wouters EF, Bast A, Hageman GJ. Poly (ADP-ribose) polymerase-1-inhibiting flavonoids attenuate cytokine release in blood from male patients with chronic obstructive pulmonary disease or type 2 diabetes. J Nutr. 2009;139(5):952-7. https://www.ncbi.nlm.nih.gov/pubmed/19321592 [IF:4.423].

Koopman R, Walrand S, Beelen M, Gijsen AP, Kies AK, Boirie Y, Saris WH, van Loon LJC. Dietary protein digestion and absorption rates and the subsequent postprandial muscle protein synthetic response do not differ between young and elderly men. J Nutr. 2009;139(9):1707-13. https://www.ncbi.nlm.nih.gov/pubmed/19625697 [IF:4.423].

Bosselaar M, Boon H, van Loon LJC, van den Broek PH, Smits P, Tack CJ. Intra-arterial AICA-riboside administration induces NO-dependent vasodilation in vivo in human skeletal muscle. Am J Physiol Endocrinol Metab. 2009;297(3):E759-66. https://www.ncbi.nlm.nih.gov/pubmed/19602584 [IF:4.248].

van Can JG, Ijzerman TH, van Loon LJC, Brouns F, Blaak EE. Reduced glycaemic and insulinaemic responses following isomaltulose ingestion: implications for postprandial substrate use. Br J Nutr. 2009;102(10):1408-13. https://www.ncbi.nlm.nih.gov/pubmed/19671200 [IF:3.784].

van Can JG, Ijzerman TH, van Loon LJC, Brouns F, Blaak EE. Reduced glycaemic and insulinaemic responses following trehalose ingestion: implications for postprandial substrate use. Br J Nutr. 2009;102(10):1395-9. https://www.ncbi.nlm.nih.gov/pubmed/19664296 [IF:3.784].

Koopman R, van Loon LJC. Aging, exercise, and muscle protein metabolism. J Appl Physiol (1985). 2009;106(6):2040-8.https://www.ncbi.nlm.nih.gov/pubmed/19131471 [IF:3.519].

Manders RJ, Praet SF, Vikstrom MH, Saris WH, van Loon LJC. Protein hydrolysate co-ingestion does not modulate 24 h glycemic control in long-standing type 2 diabetes patients. Eur J Clin Nutr. 2009;63(1):121-6. https://www.ncbi.nlm.nih.gov/pubmed/17717533 [IF:3.226].

Verdijk LB, van Loon LJC, Meijer K, Savelberg HH. One-repetition maximum strength test represents a valid means to assess leg strength in vivo in humans. J Sports Sci. 2009;27(1):59-68. https://www.ncbi.nlm.nih.gov/pubmed/19031334[IF:3.043].

Praet SF, van Loon LJC. Exercise therapy in type 2 diabetes. Acta Diabetol. 2009;46(4):263-78.https://www.ncbi.nlm.nih.gov/pubmed/19479186 [IF:2.927].

van Loon LJC, Boirie Y, Gijsen AP, Fauquant J, de Roos AL, Kies AK, Lemosquet S, Saris WH, Koopman R. The production of intrinsically labeled milk protein provides a functional tool for human nutrition research. J Dairy Sci. 2009;92(10):4812-22. https://www.ncbi.nlm.nih.gov/pubmed/19762796 [IF:2.855].

Beelen M, Berghuis J, Bonaparte B, Ballak SB, Jeukendrup AE, van Loon LJC. Carbohydrate mouth rinsing in the fed state: lack of enhancement of time-trial performance. Int J Sport Nutr Exerc Metab. 2009;19(4):400-9. https://www.ncbi.nlm.nih.gov/pubmed/19827464 [IF:2.367].

Vanschoonbeek K, Lansink M, van Laere KM, Senden JM, Verdijk LB, van Loon LJC. Slowly digestible carbohydrate sources can be used to attenuate the postprandial glycemic response to the ingestion of diabetes-specific enteral formulas. Diabetes Educ. 2009;35(4):631-40. https://www.ncbi.nlm.nih.gov/pubmed/19448045 [IF:2.138].

2008

Pelsers MM, Stellingwerff T, van Loon LJC. The role of membrane fatty-acid transporters in regulating skeletal muscle substrate use during exercise. Sports Med. 2008;38(5):387-99. https://www.ncbi.nlm.nih.gov/pubmed/18416593[IF:7.622].

Kuipers H, Van’t Hullenaar GA, Pluim BM, Overbeek SE, De Hon O, Van Breda EJ, van Loon LJC. Four weeks’ corticosteroid inhalation does not augment maximal power output in endurance athletes. Br J Sports Med. 2008;42(11):868-71. https://www.ncbi.nlm.nih.gov/pubmed/18344386 [IF:6.644].

Praet SF, van Rooij ES, Wijtvliet A, Boonman-de Winter LJ, Enneking T, Kuipers H, Stehouwer CD, van Loon LJC. Brisk walking compared with an individualised medical fitness programme for patients with type 2 diabetes: a randomised controlled trial. Diabetologia. 2008;51(5):736-46. https://www.ncbi.nlm.nih.gov/pubmed/18297259 [IF:6.358].

Praet SF, van Loon LJC. Exercise: the brittle cornerstone of type 2 diabetes treatment. Diabetologia. 2008;51(3):398-401. https://www.ncbi.nlm.nih.gov/pubmed/18183362 [IF:6.358].

Boon H, Bosselaar M, Praet SF, Blaak EE, Saris WH, Wagenmakers AJ, McGee SL, Tack CJ, Smits P, Hargreaves M, van Loon LJC. Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients. Diabetologia. 2008;51(10):1893-900. https://www.ncbi.nlm.nih.gov/pubmed/18709353 [IF:6.358].

Norton L, Parr T, Chokkalingam K, Bardsley RG, Ye H, Bell GI, Pelsers MM, van Loon LJC, Tsintzas K. Calpain-10 gene and protein expression in human skeletal muscle: effect of acute lipid-induced insulin resistance and type 2 diabetes. J Clin Endocrinol Metab. 2008;93(3):992-8. https://www.ncbi.nlm.nih.gov/pubmed/18089694 [IF:6.215].

Manders RJ, Koopman R, Beelen M, Gijsen AP, Wodzig WK, Saris WH, van Loon LJC. The muscle protein synthetic response to carbohydrate and protein ingestion is not impaired in men with longstanding type 2 diabetes. J Nutr. 2008;138(6):1079-85. https://www.ncbi.nlm.nih.gov/pubmed/18492837 [IF:4.423].

Beelen M, Tieland M, Gijsen AP, Vandereyt H, Kies AK, Kuipers H, Saris WH, Koopman R, van Loon LJC. Coingestion of carbohydrate and protein hydrolysate stimulates muscle protein synthesis during exercise in young men, with no further increase during subsequent overnight recovery. J Nutr. 2008;138(11):2198-204. https://www.ncbi.nlm.nih.gov/pubmed/18936219 [IF:4.423].

Beelen M, Koopman R, Gijsen AP, Vandereyt H, Kies AK, Kuipers H, Saris WH, van Loon LJC. Protein coingestion stimulates muscle protein synthesis during resistance-type exercise. Am J Physiol Endocrinol Metab. 2008;295(1):E70-7. https://www.ncbi.nlm.nih.gov/pubmed/18430966 [IF:4.248].

Praet SF, Jonkers RA, Schep G, Stehouwer CD, Kuipers H, Keizer HA, van Loon LJC. Long-standing, insulin-treated type 2 diabetes patients with complications respond well to short-term resistance and interval exercise training. Eur J Endocrinol. 2008;158(2):163-72. https://www.ncbi.nlm.nih.gov/pubmed/18230822 [IF:4.142].

De Feyter HM, van den Broek NM, Praet SF, Nicolay K, van Loon LJC, Prompers JJ. Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction. Eur J Endocrinol. 2008;158(5):643-53. https://www.ncbi.nlm.nih.gov/pubmed/18426822 [IF:4.142].

Koopman R, Verdijk LB, Beelen M, Gorselink M, Kruseman AN, Wagenmakers AJ, Kuipers H, van Loon LJC. Co-ingestion of leucine with protein does not further augment post-exercise muscle protein synthesis rates in elderly men. Br J Nutr. 2008;99(3):571-80. https://www.ncbi.nlm.nih.gov/pubmed/17697406 [IF:3.784].

2007

De Feyter HM, Praet SF, van den Broek NM, Kuipers H, Stehouwer CD, Nicolay K, Prompers JJ, van Loon LJC. Exercise training improves glycemic control in long-standing insulin-treated type 2 diabetic patients. Diabetes Care. 2007;30(10):2511-3. https://www.ncbi.nlm.nih.gov/pubmed/17626892 [IF:10.037].

Wendt D, van Loon LJC, Lichtenbelt WD. Thermoregulation during exercise in the heat: strategies for maintaining health and performance. Sports Med. 2007;37(8):669-82. https://www.ncbi.nlm.nih.gov/pubmed/17645370 [IF:7.622].

Koopman R, Saris WH, Wagenmakers AJ, van Loon LJC. Nutritional interventions to promote post-exercise muscle protein synthesis. Sports Med. 2007;37(10):895-906. https://www.ncbi.nlm.nih.gov/pubmed/17887813 [IF:7.622].

Hansen D, Dendale P, Berger J, van Loon LJC, Meeusen R. The effects of exercise training on fat-mass loss in obese patients during energy intake restriction. Sports Med. 2007;37(1):31-46. https://www.ncbi.nlm.nih.gov/pubmed/17190534 [IF:7.622].

Boon H, Blaak EE, Saris WH, Keizer HA, Wagenmakers AJ, van Loon LJC. Substrate source utilisation in long-term diagnosed type 2 diabetes patients at rest, and during exercise and subsequent recovery. Diabetologia. 2007;50(1):103-12. https://www.ncbi.nlm.nih.gov/pubmed/17131144 [IF:6.358].

Beulens JW, van Loon LJC, Kok FJ, Pelsers M, Bobbert T, Spranger J, Helander A, Hendriks HF. The effect of moderate alcohol consumption on adiponectin oligomers and muscle oxidative capacity: a human intervention study.Diabetologia. 2007;50(7):1388-92. https://www.ncbi.nlm.nih.gov/pubmed/17492425 [IF:6.358].

Chokkalingam K, Jewell K, Norton L, Littlewood J, van Loon LJC, Mansell P, Macdonald IA, Tsintzas K. High-fat/low-carbohydrate diet reduces insulin-stimulated carbohydrate oxidation but stimulates nonoxidative glucose disposal in humans: An important role for skeletal muscle pyruvate dehydrogenase kinase 4. J Clin Endocrinol Metab. 2007;92(1):284-92. https://www.ncbi.nlm.nih.gov/pubmed/17062764 [IF:6.215].

Rietjens SJ, Beelen M, Koopman R, van Loon LJC, Bast A, Haenen GR. A single session of resistance exercise induces oxidative damage in untrained men. Med Sci Sports Exerc. 2007;39(12):2145-51. https://www.ncbi.nlm.nih.gov/pubmed/18046185 [IF:5.222].

Boon H, Jonkers RA, Koopman R, Blaak EE, Saris WH, Wagenmakers AJ, van Loon LJC. Substrate source use in older, trained males after decades of endurance training. Med Sci Sports Exerc. 2007;39(12):2160-70. https://www.ncbi.nlm.nih.gov/pubmed/18046187 [IF:5.222].

Koopman R, Pennings B, Zorenc AH, van Loon LJC. Protein ingestion further augments S6K1 phosphorylation in skeletal muscle following resistance type exercise in males. J Nutr. 2007;137(8):1880-6. https://www.ncbi.nlm.nih.gov/pubmed/17634259 [IF:4.423].

Verdijk LB, Koopman R, Schaart G, Meijer K, Savelberg HH, van Loon LJC. Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly. Am J Physiol Endocrinol Metab. 2007;292(1):E151-7. https://www.ncbi.nlm.nih.gov/pubmed/16926381 [IF:4.248].

Stellingwerff T, Boon H, Jonkers RA, Senden JM, Spriet LL, Koopman R, van Loon LJC. Significant intramyocellular lipid use during prolonged cycling in endurance-trained males as assessed by three different methodologies. Am J Physiol Endocrinol Metab. 2007;292(6):E1715-23. https://www.ncbi.nlm.nih.gov/pubmed/17299080 [IF:4.248].

Koopman R, Beelen M, Stellingwerff T, Pennings B, Saris WH, Kies AK, Kuipers H, van Loon LJC. Coingestion of carbohydrate with protein does not further augment postexercise muscle protein synthesis. Am J Physiol Endocrinol Metab. 2007;293(3):E833-42. https://www.ncbi.nlm.nih.gov/pubmed/17609259 [IF:4.248].

Pelsers MM, Tsintzas K, Boon H, Jewell K, Norton L, Luiken JJ, Glatz JF, van Loon LJC. Skeletal muscle fatty acid transporter protein expression in type 2 diabetes patients compared with overweight, sedentary men and age-matched, endurance-trained cyclists. Acta Physiol (Oxf). 2007;190(3):209-19. https://www.ncbi.nlm.nih.gov/pubmed/17394567 [IF:3.695].

Praet SF, van Loon LJC. Optimizing the therapeutic benefits of exercise in Type 2 diabetes. J Appl Physiol (1985). 2007;103(4):1113-20. https://www.ncbi.nlm.nih.gov/pubmed/17656625 [IF:3.519].

Stellingwerff T, Boon H, Gijsen AP, Stegen JH, Kuipers H, van Loon LJC. Carbohydrate supplementation during prolonged cycling exercise spares muscle glycogen but does not affect intramyocellular lipid use. Pflugers Arch. 2007;454(4):635-47. https://www.ncbi.nlm.nih.gov/pubmed/17333244 [IF:3.128].

Galbo H, Tobin L, van Loon LJC. Responses to acute exercise in type 2 diabetes, with an emphasis on metabolism and interaction with oral hypoglycemic agents and food intake. Appl Physiol Nutr Metab. 2007;32(3):567-75. https://www.ncbi.nlm.nih.gov/pubmed/17510698 [IF:2.624].

Tunstall RJ, McAinch AJ, Hargreaves M, van Loon LJC, Cameron-Smith D. Reduced plasma free fatty acid availability during exercise: effect on gene expression. Eur J Appl Physiol. 2007;99(5):485-93. https://www.ncbi.nlm.nih.gov/pubmed/17186295 [IF:2.567].

van Loon LJC, Kies AK, Saris WH. Protein and protein hydrolysates in sports nutrition. Int J Sport Nutr Exerc Metab. 2007;17 Suppl:S1-4. https://www.ncbi.nlm.nih.gov/pubmed/18577770 [IF:2.367].

van Loon LJC. Application of protein or protein hydrolysates to improve postexercise recovery. Int J Sport Nutr Exerc Metab. 2007;17 Suppl:S104-17. https://www.ncbi.nlm.nih.gov/pubmed/18577771 [IF:2.367].

Pelsers MMAL, Tsintzas K, Boon H, Jewell K, Norton L, Luiken JJFP, Glatz JFC, Van Loon LJC. [Expression of fatty acid transporters in the skeletal muscle of type 2 diabetes patients compared with age-matched sedentary men and endurance-trained cyclists] – Expressie van vetzuurtransporters in skeletspier van type-2- diabetespatiënten in vergelijking met sedentaire mannen en leeftijd-gematchte getrainde wielrenners. Nederlands Tijdschrift voor Klinische Chemie en Laboratoriumgeneeskunde. 2007;32(4):268-70. https://www.nvkc.nl/sites/default/files/NTKC/2007-4-p268-270.pdf.

van Loon LJC. Amino acids as pharmaco-nutrients for the treatment of type 2 diabetes. Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 2007;7(1):39-48. http://www.eurekaselect.com/77682/article/amino-acids-pharmaco-nutrients-treatment-type-2-diabetes.

2006

Manders RJ, Praet SF, Meex RC, Koopman R, de Roos AL, Wagenmakers AJ, Saris WH, van Loon LJC. Protein hydrolysate/leucine co-ingestion reduces the prevalence of hyperglycemia in type 2 diabetic patients. Diabetes Care. 2006;29(12):2721-2. https://www.ncbi.nlm.nih.gov/pubmed/17130211 [IF:10.037].

Koopman R, Verdijk L, Manders RJ, Gijsen AP, Gorselink M, Pijpers E, Wagenmakers AJ, van Loon LJC. Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men. Am J Clin Nutr. 2006;84(3):623-32. https://www.ncbi.nlm.nih.gov/pubmed/16960178 [IF:7.506].

Praet SF, Manders RJ, Meex RC, Lieverse AG, Stehouwer CD, Kuipers H, Keizer HA, van Loon LJC. Glycaemic instability is an underestimated problem in Type II diabetes. Clin Sci (Lond). 2006;111(2):119-26. https://www.ncbi.nlm.nih.gov/pubmed/16613586 [IF:5.315].

Praet SF, Manders RJ, Lieverse AG, Kuipers H, Stehouwer CD, Keizer HA, van Loon LJC. Influence of acute exercise on hyperglycemia in insulin-treated type 2 diabetes. Med Sci Sports Exerc. 2006;38(12):2037-44. https://www.ncbi.nlm.nih.gov/pubmed/17146308 [IF:5.222].

Kaastra B, Manders RJ, Van Breda E, Kies A, Jeukendrup AE, Keizer HA, Kuipers H, van Loon LJC. Effects of increasing insulin secretion on acute postexercise blood glucose disposal. Med Sci Sports Exerc. 2006;38(2):268-75. https://www.ncbi.nlm.nih.gov/pubmed/16531895 [IF:5.222].

Vanschoonbeek K, Thomassen BJ, Senden JM, Wodzig WK, van Loon LJC. Cinnamon supplementation does not improve glycemic control in postmenopausal type 2 diabetes patients. J Nutr. 2006;136(4):977-80. https://www.ncbi.nlm.nih.gov/pubmed/16549460 [IF:4.423].

Manders RJ, Koopman R, Sluijsmans WE, van den Berg R, Verbeek K, Saris WH, Wagenmakers AJ, van Loon LJC. Co-ingestion of a protein hydrolysate with or without additional leucine effectively reduces postprandial blood glucose excursions in Type 2 diabetic men. J Nutr. 2006;136(5):1294-9. https://www.ncbi.nlm.nih.gov/pubmed/16614419[IF:4.423].

Koopman R, Zorenc AH, Gransier RJ, Cameron-Smith D, van Loon LJC. Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type II muscle fibers. Am J Physiol Endocrinol Metab. 2006;290(6):E1245-52. https://www.ncbi.nlm.nih.gov/pubmed/16434552 [IF:4.248].

Bonen A, Dohm GL, van Loon LJC. Lipid metabolism, exercise and insulin action. Essays Biochem. 2006;42:47-59.https://www.ncbi.nlm.nih.gov/pubmed/17144879 [IF:3.712].

van Loon LJC, Goodpaster BH. Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state. Pflugers Arch. 2006;451(5):606-16. https://www.ncbi.nlm.nih.gov/pubmed/16155759 [IF:3.128].

Panis B, Bakker JA, Sels JP, Spaapen LJ, van Loon LJC, Rubio-Gozalbo ME. Untreated classical galactosemia patient with mild phenotype. Mol Genet Metab. 2006;89(3):277-9. https://www.ncbi.nlm.nih.gov/pubmed/16621642 [IF:2.974].

Koopman R, Manders RJ, Jonkers RA, Hul GB, Kuipers H, van Loon LJC. Intramyocellular lipid and glycogen content are reduced following resistance exercise in untrained healthy males. Eur J Appl Physiol. 2006;96(5):525-34. https://www.ncbi.nlm.nih.gov/pubmed/16369816 [IF:2.567].

Praet SF, De Feyter HM, Jonkers RA, Nicolay K, van Pul C, Kuipers H, van Loon LJC, Prompers JJ. 31P MR spectroscopy and in vitro markers of oxidative capacity in type 2 diabetes patients. Magn Reson Mater Phy. 2006;19(6):321-31. https://www.ncbi.nlm.nih.gov/pubmed/17180611 [IF:2.180].

Timmermans RJ, Saris WH, van Loon LJC. [Insulin resistance: the role of intramuscular triglyceride and the importance of physical activity] – Insulineresistentie: de rol van intramusculair triacylglycerol en het nut van fysieke inspanning.Ned Tijdschr Geneeskd. 2006;150(3):122-7. https://www.ncbi.nlm.nih.gov/pubmed/16463611.

Hansen D, Dendale P, Van Loon LJC, Meeusen R. [Optimalization of training modalities for patients with cardiac disease and obesity] – Optimalisatie van trainingsmodaliteiten voor hart- en obesitaspatië nten. Geneeskunde en Sport. 2006;39(4):145-54. https://www.sportengeneeskunde.nl/artikelen/434-optimalisatie-van-trainingsmodaliteiten-voor-hart-en-obesitaspatienten.html.

2005

Manders RJ, Wagenmakers AJ, Koopman R, Zorenc AH, Menheere PP, Schaper NC, Saris WH, van Loon LJC. Co-ingestion of a protein hydrolysate and amino acid mixture with carbohydrate improves plasma glucose disposal in patients with type 2 diabetes. Am J Clin Nutr. 2005;82(1):76-83. https://www.ncbi.nlm.nih.gov/pubmed/16002803[IF:7.506].

van Loon LJC, Manders RJ, Koopman R, Kaastra B, Stegen JH, Gijsen AP, Saris WH, Keizer HA. Inhibition of adipose tissue lipolysis increases intramuscular lipid use in type 2 diabetic patients. Diabetologia. 2005;48(10):2097-107. https://www.ncbi.nlm.nih.gov/pubmed/16096823 [IF:6.358].

van Loon LJC, Thomason-Hughes M, Constantin-Teodosiu D, Koopman R, Greenhaff PL, Hardie DG, Keizer HA, Saris WH, Wagenmakers AJ. Inhibition of adipose tissue lipolysis increases intramuscular lipid and glycogen use in vivo in humans. Am J Physiol Endocrinol Metab. 2005;289(3):E482-93. https://www.ncbi.nlm.nih.gov/pubmed/15886227[IF:4.248].

Koopman R, Wagenmakers AJ, Manders RJ, Zorenc AH, Senden JM, Gorselink M, Keizer HA, van Loon LJC. Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects. Am J Physiol Endocrinol Metab. 2005;288(4):E645-53. https://www.ncbi.nlm.nih.gov/pubmed/15562251[IF:4.248].

Punyadeera C, Zorenc AH, Koopman R, McAinch AJ, Smit E, Manders R, Keizer HA, Cameron-Smith D, van Loon LJC. The effects of exercise and adipose tissue lipolysis on plasma adiponectin concentration and adiponectin receptor expression in human skeletal muscle. Eur J Endocrinol. 2005;152(3):427-36. https://www.ncbi.nlm.nih.gov/pubmed/15757860 [IF:4.142].

Koopman R, Manders RJ, Zorenc AH, Hul GB, Kuipers H, Keizer HA, van Loon LJC. A single session of resistance exercise enhances insulin sensitivity for at least 24 h in healthy men. Eur J Appl Physiol. 2005;94(1-2):180-7. https://www.ncbi.nlm.nih.gov/pubmed/15761746 [IF:2.567].

2004

van Loon LJC, Murphy R, Oosterlaar AM, Cameron-Smith D, Hargreaves M, Wagenmakers AJ, Snow R. Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscle. Clin Sci (Lond). 2004;106(1):99-106. https://www.ncbi.nlm.nih.gov/pubmed/14507259 [IF:5.315].

van Loon LJC. Intramyocellular triacylglycerol as a substrate source during exercise. Proc Nutr Soc. 2004;63(2):301-7. https://www.ncbi.nlm.nih.gov/pubmed/15294047 [IF:4.797].

van Loon LJC, Koopman R, Manders R, van der Weegen W, van Kranenburg GP, Keizer HA. Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes. Am J Physiol Endocrinol Metab. 2004;287(3):E558-65. https://www.ncbi.nlm.nih.gov/pubmed/15165998 [IF:4.248].

Koopman R, Pannemans DL, Jeukendrup AE, Gijsen AP, Senden JM, Halliday D, Saris WH, van Loon LJC, Wagenmakers AJ. Combined ingestion of protein and carbohydrate improves protein balance during ultra-endurance exercise. Am J Physiol Endocrinol Metab. 2004;287(4):E712-20. https://www.ncbi.nlm.nih.gov/pubmed/15165999 [IF:4.248].

van Loon LJC. Use of intramuscular triacylglycerol as a substrate source during exercise in humans. J Appl Physiol (1985). 2004;97(4):1170-87. https://www.ncbi.nlm.nih.gov/pubmed/15358749 [IF:3.519].

Saris WH, van Loon LJC. [Nutrition and health–nutrition and performance in sports] – Voeding en gezondheid–voeding en sportprestaties. Ned Tijdschr Geneeskd. 2004;148(15):708-12. https://www.ncbi.nlm.nih.gov/pubmed/15119203.

2003

van Loon LJC, Kruijshoop M, Menheere PP, Wagenmakers AJ, Saris WH, Keizer HA. Amino acid ingestion strongly enhances insulin secretion in patients with long-term type 2 diabetes. Diabetes Care. 2003;26(3):625-30. https://www.ncbi.nlm.nih.gov/pubmed/12610012 [IF:10.037].

van Loon LJC, Oosterlaar AM, Hartgens F, Hesselink MK, Snow RJ, Wagenmakers AJ. Effects of creatine loading and prolonged creatine supplementation on body composition, fuel selection, sprint and endurance performance in humans. Clin Sci (Lond). 2003;104(2):153-62. https://www.ncbi.nlm.nih.gov/pubmed/12546637 [IF:5.315].

van Loon LJC, Koopman R, Stegen JH, Wagenmakers AJ, Keizer HA, Saris WH. Intramyocellular lipids form an important substrate source during moderate intensity exercise in endurance-trained males in a fasted state. J Physiol. 2003;553(Pt 2):611-25. https://www.ncbi.nlm.nih.gov/pubmed/14514877 [IF:4.898].

van Loon LJC, Schrauwen-Hinderling VB, Koopman R, Wagenmakers AJ, Hesselink MK, Schaart G, Kooi ME, Saris WH. Influence of prolonged endurance cycling and recovery diet on intramuscular triglyceride content in trained males. Am J Physiol Endocrinol Metab. 2003;285(4):E804-11. https://www.ncbi.nlm.nih.gov/pubmed/12783774[IF:4.248].

Schrauwen-Hinderling VB, van Loon LJC, Koopman R, Nicolay K, Saris WH, Kooi ME. Intramyocellular lipid content is increased after exercise in nonexercising human skeletal muscle. J Appl Physiol (1985). 2003;95(6):2328-32. https://www.ncbi.nlm.nih.gov/pubmed/12923116 [IF:3.519].

van Loon LJC, Koopman R, Schrauwen P, Stegen J, Wagenmakers AJ. The use of the [1,2-13C]acetate recovery factor in metabolic research. Eur J Appl Physiol. 2003;89(3-4):377-83. https://www.ncbi.nlm.nih.gov/pubmed/12682837 [IF:2.567].

2002

van Loon LJC. [The human motor: Food as energy] – De menselijke motor: Voeding als energie. Geneeskunde en Sport. 2002;35(3):7-10. https://www.sportengeneeskunde.nl/artikelen/332-de-menselijke-motor-voeding-als-energie.html.

2001

van Loon LJC, Greenhaff PL, Constantin-Teodosiu D, Saris WH, Wagenmakers AJ. The effects of increasing exercise intensity on muscle fuel utilisation in humans. J Physiol. 2001;536(Pt 1):295-304. https://www.ncbi.nlm.nih.gov/pubmed/11579177 [IF:4.898].

Jentjens RL, van Loon LJC, Mann CH, Wagenmakers AJ, Jeukendrup AE. Addition of protein and amino acids to carbohydrates does not enhance postexercise muscle glycogen synthesis. J Appl Physiol (1985). 2001;91(2):839-46. https://www.ncbi.nlm.nih.gov/pubmed/11457801 [IF:3.519].

2000

van Loon LJC, van Rooijen JJ, Niesen B, Verhagen H, Saris WH, Wagenmakers AJ. Effects of acute (-)-hydroxycitrate supplementation on substrate metabolism at rest and during exercise in humans. Am J Clin Nutr. 2000;72(6):1445-50. https://www.ncbi.nlm.nih.gov/pubmed/11101469 [IF:7.506].

van Loon LJC, Saris WH, Verhagen H, Wagenmakers AJ. Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate. Am J Clin Nutr. 2000;72(1):96-105. https://www.ncbi.nlm.nih.gov/pubmed/10871567 [IF:7.506].

van Loon LJC, Saris WH, Kruijshoop M, Wagenmakers AJ. Maximizing postexercise muscle glycogen synthesis: carbohydrate supplementation and the application of amino acid or protein hydrolysate mixtures. Am J Clin Nutr. 2000;72(1):106-11. https://www.ncbi.nlm.nih.gov/pubmed/10871568 [IF:7.506].

van Loon LJC, Kruijshoop M, Verhagen H, Saris WH, Wagenmakers AJ. Ingestion of protein hydrolysate and amino acid-carbohydrate mixtures increases postexercise plasma insulin responses in men. J Nutr. 2000;130(10):2508-13. https://www.ncbi.nlm.nih.gov/pubmed/11015482 [IF:4.423].

1999

van Loon LJC, Jeukendrup AE, Saris WH, Wagenmakers AJ. Effect of training status on fuel selection during submaximal exercise with glucose ingestion. J Appl Physiol (1985). 1999;87(4):1413-20. https://www.ncbi.nlm.nih.gov/pubmed/10517772 [IF:3.519].