Meex RCR, Blaak EE, van Loon LJC. Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes. Obes Rev. 2019;20(9):1205-17.https://www.ncbi.nlm.nih.gov/pubmed/31240819 [IF:8.483].

van Dijk DPJ, Horstman AMH, Smeets JSJ, den Dulk M, Grabsch HI, Dejong CHC, Rensen SS, Olde Damink SWM, van Loon LJC. Tumour-specific and organ-specific protein synthesis rates in patients with pancreatic cancer. J Cachexia Sarcopenia Muscle. 2019;10(3):549-56. https://www.ncbi.nlm.nih.gov/pubmed/30868736 [IF:7.894].

Kneppers AEM, Haast RAM, Langen RCJ, Verdijk LB, Leermakers PA, Gosker HR, van Loon LJC, Lainscak M, Schols A. Distinct skeletal muscle molecular responses to pulmonary rehabilitation in chronic obstructive pulmonary disease: a cluster analysis. J Cachexia Sarcopenia Muscle. 2019;10(2):311-22. https://www.ncbi.nlm.nih.gov/pubmed/30657653[IF:7.894].

Trommelen J, Betz MW, van Loon LJC. The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise. Sports Med. 2019;49(2):185–97. https://www.ncbi.nlm.nih.gov/pubmed/30659499 [IF:7.622].

Knuiman P, van Loon LJC, Wouters J, Hopman M, Mensink M. Protein supplementation elicits greater gains in maximal oxygen uptake capacity and stimulates lean mass accretion during prolonged endurance training: a double-blind randomized controlled trial. Am J Clin Nutr. 2019;110(2):508-18. https://www.ncbi.nlm.nih.gov/pubmed/31240303 [IF:7.506].

Fuchs CJ, Hermans WJH, Holwerda AM, Smeets JSJ, Senden JM, van Kranenburg J, Gijsen AP, Wodzig W, Schierbeek H, Verdijk LB, van Loon LJC. Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial. Am J Clin Nutr. 2019;110(4):862-72. https://www.ncbi.nlm.nih.gov/pubmed/31250889 [IF:7.506].

Kramer IF, Blokhuis TJ, Verdijk LB, van Loon LJC, Poeze M. Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients. Nutr Rev. 2019;77(4):254–66. https://www.ncbi.nlm.nih.gov/pubmed/30624706[IF:6.428].

Horstman AMH, Kouw IWK, van Dijk JW, Hamer HM, Groen BBL, van Kranenburg J, Gorissen SHM, van Loon LJC. The muscle protein synthetic response to whey protein ingestion is greater in middle-aged women when compared with men. J Clin Endocrinol Metab. 2019;104(4):994–1004. https://www.ncbi.nlm.nih.gov/pubmed/30423113 [IF:6.215].

Mason SA, Rasmussen B, van Loon LJC, Salmon J, Wadley GD. Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in people with type 2 diabetes: Findings of a randomized cross-over trial. Diabetes Obes Metab. 2019;21(3):674-82. https://www.ncbi.nlm.nih.gov/pubmed/30394006 [IF:5.888].

Kouw IWK, Groen BBL, Smeets JSJ, Kramer IF, van Kranenburg JMX, Nilwik R, Geurts JAP, Ten Broeke RHM, Poeze M, van Loon LJC, Verdijk LB. One Week of Hospitalization Following Elective Hip Surgery Induces Substantial Muscle Atrophy in Older Patients. J Am Med Dir Assoc. 2019;20:35-42. https://www.ncbi.nlm.nih.gov/pubmed/30108034 [IF:5.449].

Smiles WJ, Churchward-Venne TA, van Loon LJC, Hawley JA, Camera DM. A single bout of strenuous exercise overcomes lipid-induced anabolic resistance to protein ingestion in overweight, middle-aged men. FASEB J. 2019;33(6):7009-17. https://www.ncbi.nlm.nih.gov/pubmed/30840513 [IF:5.337].

Kneppers A, Leermakers P, Pansters N, Backx E, Gosker H, van Loon LJC, Schols A, Langen R, Verdijk L. Coordinated regulation of skeletal muscle mass and metabolic plasticity during recovery from disuse. FASEB J. 2019;33(1):1288-98. https://www.ncbi.nlm.nih.gov/pubmed/30133324 [IF:5.337].

Shad BJ, Thompson JL, Holwerda AM, Stocks B, Elhassan YS, Philp A, van Loon LJC, Wallis GA. One Week of Step Reduction Lowers Myofibrillar Protein Synthesis Rates in Young Men. Med Sci Sports Exerc. 2019;51(10):2125-34. https://www.ncbi.nlm.nih.gov/pubmed/31083048 [IF:5.222].

Nyakayiru J, Fuchs CJ, Trommelen J, Smeets JSJ, Senden JM, Gijsen AP, Zorenc AH, van Loon LJC, Verdijk LB. Blood Flow Restriction Only Increases Myofibrillar Protein Synthesis with Exercise. Med Sci Sports Exerc. 2019;51(6):1137-45. https://www.ncbi.nlm.nih.gov/pubmed/30694972 [IF:5.222].

Jonvik KL, Paulussen KJM, Danen SL, Ceelen IJM, Horstman AM, Wardenaar FC, van Loon LJC, van Dijk JW. Protein Supplementation Does Not Augment Adaptations to Endurance Exercise Training. Med Sci Sports Exerc. 2019;51(10):2041-9. https://www.ncbi.nlm.nih.gov/pubmed/31525168 [IF:5.222].

Jonvik KL, Lenaerts K, Smeets JSJ, Kolkman JJ, van Loon LJC, Verdijk LB. Sucrose but Not Nitrate Ingestion Reduces Strenuous Cycling–induced Intestinal Injury. Med Sci Sports Exerc. 2019;51(3):436-44. https://www.ncbi.nlm.nih.gov/pubmed/30299412 [IF:5.222].

Petrick HL, Pignanelli C, Barbeau PA, Churchward-Venne TA, Dennis K, van Loon LJC, Burr JF, Goossens GH, Holloway GP. Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2 O2 emission rates in human skeletal muscle. J Physiol. 2019;597(15):3985-97. https://www.ncbi.nlm.nih.gov/pubmed/31194254 [IF:4.898].

Fuchs CJ, Gonzalez JT, van Loon LJC. Fructose co-ingestion to increase carbohydrate availability in athletes. J Physiol. 2019;597(14):3549-60. https://www.ncbi.nlm.nih.gov/pubmed/31166604 [IF:4.898].

Groenendijk I, den Boeft L, van Loon LJC, de Groot LCPM. High versus low dietary protein intake and bone health in older adults: A systematic review and meta-analysis. Computational and Structural Biotechnology Journal. 2019;17:1101–12. http://www.sciencedirect.com/science/article/pii/S2001037019301448 [IF:4.720].

Kouw IWK, van Dijk JW, Horstman AMH, Kramer IF, Goessens JPB, van Dielen FMH, Verdijk LB, van Loon LJC. Basal and Postprandial Myofibrillar Protein Synthesis Rates Do Not Differ between Lean and Obese Middle-Aged Men. J Nutr. 2019;149(9):1533–42. https://www.ncbi.nlm.nih.gov/pubmed/31174213 [IF:4.423].

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig W, Verdijk LB, van Loon LJC. Dose-Dependent Increases in Whole-Body Net Protein Balance and Dietary Protein-Derived Amino Acid Incorporation into Myofibrillar Protein During Recovery from Resistance Exercise in Older Men. J Nutr. 2019;149(2):221–30. https://www.ncbi.nlm.nih.gov/pubmed/30722014 [IF:4.423].

Churchward-Venne TA, Pinckaers PJM, Smeets JSJ, Peeters WM, Zorenc AH, Schierbeek H, Rollo I, Verdijk LB, van Loon LJC. Myofibrillar and Mitochondrial Protein Synthesis Rates Do Not Differ in Young Men Following the Ingestion of Carbohydrate with Milk Protein, Whey, or Micellar Casein after Concurrent Resistance- and Endurance-Type Exercise. J Nutr. 2019;149(2):198–209. https://www.ncbi.nlm.nih.gov/pubmed/30698725 [IF:4.423].

Churchward-Venne TA, Pinckaers PJM, Smeets JSJ, Peeters WM, Zorenc AH, Schierbeek H, Rollo I, Verdijk LB, van Loon LJC. Myofibrillar and Mitochondrial Protein Synthesis Rates Do Not Differ in Young Men Following the Ingestion of Carbohydrate with Whey, Soy, or Leucine-Enriched Soy Protein after Concurrent Resistance- and Endurance-Type Exercise. J Nutr. 2019;149(2):210–20. https://www.ncbi.nlm.nih.gov/pubmed/30698812 [IF:4.423].

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig W, Verdijk LB, de Groot L, van Loon LJC. Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men. Am J Physiol Endocrinol Metab. 2019;317(3):E473-E82. https://www.ncbi.nlm.nih.gov/pubmed/31112406 [IF:4.248].

Dirks ML, Smeets JSJ, Holwerda AM, Kouw IWK, Marzuca-Nassr GN, Gijsen AP, Holloway GP, Verdijk LB, van Loon LJC. Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest. Am J Physiol Endocrinol Metab. 2019;316(3):E536-E45. https://www.ncbi.nlm.nih.gov/pubmed/30645176 [IF:4.248].

Trommelen J, Holwerda AM, Nyakayiru J, Gorissen SHM, Rooyackers O, Burd NA, Boirie Y, van Loon LJC. The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation. Am J Physiol Endocrinol Metab. 2019;317(3):E433-E4 (Letter to the Editor). https://www.ncbi.nlm.nih.gov/pubmed/31423800 [IF:4.248].

Hendriks FK, Smeets JSJ, van der Sande FM, Kooman JP, van Loon LJC. Dietary Protein and Physical Activity Interventions to Support Muscle Maintenance in End-Stage Renal Disease Patients on Hemodialysis. Nutrients. 2019;11(12):2972. https://www.mdpi.com/2072-6643/11/12/2972 [IF:4.187].

Vaes AMM, Brouwer-Brolsma EM, Toussaint N, de Regt M, Tieland M, van Loon LJC, de Groot LCPGM. The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults. Eur J Nutr. 2019;58:1173–81. https://www.ncbi.nlm.nih.gov/pubmed/29691654 [IF:3.937].

van Vliet S, Beals JW, Holwerda AM, Emmons RS, Goessens JP, Paluska SA, De Lisio M, van Loon LJC, Burd NA. Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men. J Appl Physiol (1985). 2019;127(6):1792-801. https://www.ncbi.nlm.nih.gov/pubmed/31725358 [IF:3.519].

Snijders T, Leenders M, de Groot L, van Loon LJC, Verdijk LB. Muscle mass and strength gains following 6months of resistance type exercise training are only partly preserved within one year with autonomous exercise continuation in older adults. Exp Gerontol. 2019;121:71-8. https://www.ncbi.nlm.nih.gov/pubmed/30978433 [IF:3.491].

Horstman AMH, Backx EMP, Smeets JSJ, Marzuca-Nassr GN, van Kranenburg J, de Boer D, Dolmans J, Snijders T, Verdijk LB, de Groot L, van Loon LJC. Nandrolone decanoate administration does not attenuate muscle atrophy during a short period of disuse. PLoS One. 2019;14(1):e0210823. https://www.ncbi.nlm.nih.gov/pubmed/30689637 [IF:3.394].

Smeets JSJ, Horstman AMH, Vles GF, Emans PJ, Goessens JPB, Gijsen AP, van Kranenburg JMX, van Loon LJC. Protein synthesis rates of muscle, tendon, ligament, cartilage, and bone tissue in vivo in humans. PLoS One. 2019;14(11):e0224745. https://www.ncbi.nlm.nih.gov/pubmed/31697717 [IF:3.394].

Brinkmans NYJ, Iedema N, Plasqui G, Wouters L, Saris WHM, van Loon LJC, van Dijk JW. Energy expenditure and dietary intake in professional football players in the Dutch Premier League: Implications for nutritional counselling. J Sports Sci. 2019;37(24):2759-67. https://www.ncbi.nlm.nih.gov/pubmed/30773995 [IF:3.043].

Boujemaa H, Yilmaz A, Robic B, Koppo K, Claessen G, Frederix I, Dendale P, Voller H, van Loon LJC, Hansen D. The effect of minimally invasive surgical aortic valve replacement on postoperative pulmonary and skeletal muscle function. Exp Physiol. 2019;104(6):855-65. https://www.ncbi.nlm.nih.gov/pubmed/30938881 [IF:2.937].

Weijzen MEG, Kouw IWK, Verschuren AAJ, Muyters R, Geurts JA, Emans PJ, Geerlings P, Verdijk LB, van Loon LJC. Protein Intake Falls below 0.6 g*kg-1*d-1 in Healthy, Older Patients Admitted for Elective Hip or Knee Arthroplasty. J Nutr Health Aging. 2019;23(3):299-305. https://www.ncbi.nlm.nih.gov/pubmed/30820520 [IF:2.935].

Sipers W, de Blois W, Schols J, van Loon LJC, Verdijk LB. Sarcopenia Is Related to Mortality in the Acutely Hospitalized Geriatric Patient. J Nutr Health Aging. 2019;23(2):128-37. https://www.ncbi.nlm.nih.gov/pubmed/30697621 [IF:2.935].

Hangelbroek RWJ, Vaes AMM, Boekschoten MV, Verdijk LB, Hooiveld G, van Loon LJC, de Groot LCPGM, Kersten S. No effect of 25-hydroxyvitamin D supplementation on the skeletal muscle transcriptome in vitamin D deficient frail older adults. BMC Geriatr. 2019;19(1):151. https://www.ncbi.nlm.nih.gov/pubmed/31138136 [IF:2.866].

Leermakers PA, Kneppers AEM, Schols A, Kelders M, de Theije CC, Verdijk LB, van Loon LJC, Langen RCJ, Gosker HR. Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation. Muscle Nerve. 2019;60(6):769-78. https://www.ncbi.nlm.nih.gov/pubmed/31495926 [IF:2.560].

McKenna CF, Salvador AF, Hendriks FK, Harris APY, van Loon LJC, Burd NA. Exercising to offset muscle mass loss in hemodialysis patients: The disconnect between intention and intervention. Semin Dial. 2019;32(4):379-85. https://www.ncbi.nlm.nih.gov/pubmed/30903629 [IF:1.671].

Wickham KA, McCarthy DG, Pereira JM, Cervone DT, Verdijk LB, van Loon LJC, Power GA, Spriet LL. No effect of beetroot juice supplementation on exercise economy and performance in recreationally active females despite increased torque production. Physiol Rep. 2019;7(2):e13982. https://www.ncbi.nlm.nih.gov/pubmed/30653856.

Snijders T, Trommelen J, Kouw IWK, Holwerda AM, Verdijk LB, van Loon LJC. The Impact of Pre-sleep Protein Ingestion on the Skeletal Muscle Adaptive Response to Exercise in Humans: An Update. Front Nutr. 2019;6(17). https://www.frontiersin.org/article/10.3389/fnut.2019.00017.

41 Publications