Type 2 diabetes is a chronic metabolic disease which currently affects approximately 6% of the world population. Type 2 diabetes is primarily characterized by hyperglycemia which is the result of insulin deficiency or reduced insulin sensitivity. Besides the conventional pharmacological treatment of this disease, lifestyle interventions have shown to be successful in improving glycemic control in this population.

Protein and amino acid co-ingestion has been proposed as an effective nutritional strategy to stimulate postprandial insulin secretion, improve glucose disposal and, as such, to improve glycemic control in type 2 diabetes patients. This thesis evaluates the efficacy of such nutritional interventions to improve glucose homeostasis in type 2 diabetes patients.

Defence date: 14/11/08

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Manders, R. J. F.
Manders, R. J. F.
University of Surrey