Aging is associated with muscle mass and strength loss. This thesis found that resistance-type exercise increases muscle protein synthesis rates, leading to an increase in muscle mass and strength over time. Dietary protein intake further increases post-exercise muscle protein synthesis rates and older individuals require 30-45 g to achieve a near-maximal response.

In the case that an older individual cannot ingest such large amounts of protein, the thesis found that free leucine co-ingested with 15 g protein also stimulates post-exercise muscle protein synthesis. Lastly, exercise combined with pre-sleep protein ingestion further increases muscle protein synthesis rates during overnight sleep.

Defence date: 21/03/2019

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Holwerda, A. M.
Holwerda, A. M.
Post-doctoral Researcher
Maastricht University